B
Bing Ni
Researcher at Third Military Medical University
Publications - 180
Citations - 4316
Bing Ni is an academic researcher from Third Military Medical University. The author has contributed to research in topics: Cytotoxic T cell & Immune system. The author has an hindex of 29, co-authored 167 publications receiving 3302 citations. Previous affiliations of Bing Ni include Chinese Ministry of Education & Academy of Military Medical Sciences.
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Journal ArticleDOI
Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples
Wenfei Jin,Qingsong Tang,Mimi Wan,Kairong Cui,Yi Zhang,Yi Zhang,Gang Ren,Gang Ren,Bing Ni,Jeffrey Sklar,Teresa M. Przytycka,Richard W. Childs,David Levens,Keji Zhao +13 more
TL;DR: In this article, a single-cell DNase sequencing (scDNase-seq) strategy was proposed for detection of genome-wide hypersensitive sites (DHSs) in single cells.
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Circular RNA: a novel biomarker and therapeutic target for human cancers.
TL;DR: The most recent research into tumor-related circRNAs is discussed, providing a comprehensive summary of the expression or/and function of thesecircRNAs and proposing rational perspectives on the potential clinical application of circRNas as helpful biomarkers or therapeutic targets in human tumors.
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An Increased Abundance of Tumor-Infiltrating Regulatory T Cells Is Correlated with the Progression and Prognosis of Pancreatic Ductal Adenocarcinoma
Yichen Tang,Xuejun Xu,Shixiang Guo,Chaobin Zhang,Yan Tang,Yi Tian,Bing Ni,Binfeng Lu,Huaizhi Wang +8 more
TL;DR: Tregs may promote PDA progression by inhibiting the antitumor immunity of CD8+ T cells at local intratumoral sites, and a high proportion of Tregs in tumor tissues may reflect suppressed antitumors immunity.
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Downregulated miR-506 expression facilitates pancreatic cancer progression and chemoresistance via SPHK1/Akt/NF-κB signaling
Jianjun Li,Hao Wu,Wenhua Li,Li Yin,Shixiang Guo,Xuejun Xu,Yongsheng Ouyang,Zhiping Zhao,Songsong Liu,Yin Tian,Z Tian,Jingfang Ju,Bing Ni,Huaizhi Wang +13 more
TL;DR: The data suggest that miR-506 acts as a tumor suppressor miRNA and is epigenetically silenced in pancreatic cancer.
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Single-cell chromatin immunocleavage sequencing (scChIC-seq) to profile histone modification.
Wai Lim Ku,Kosuke Nakamura,Weiwu Gao,Weiwu Gao,Kairong Cui,Gangqing Hu,Qingsong Tang,Bing Ni,Keji Zhao +8 more
TL;DR: Covalent linking of a histone-modification-specific antibody to MNase allows for the isolation of fragments with the desired histone mark, which can be amplified and sequenced, and is sensitive enough to profile histone modifications in single cells.