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Bing Xu
Researcher at Université de Montréal
Publications - 28
Citations - 51147
Bing Xu is an academic researcher from Université de Montréal. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 14, co-authored 17 publications receiving 38405 citations. Previous affiliations of Bing Xu include Facebook.
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Journal ArticleDOI
Synthesis and biological evaluation of novel sinomenine derivatives as anti-inflammatory and analgesic agent
Feng Gao,Ziqi Dai,Tong-Tian Zhang,Yuhao Gu,Desheng Cai,Min-qiang Lu,Zijie Zhang,Qinling Zeng,Bingxian Shang,Bing Xu,Haimin Lei +10 more
TL;DR: In this article , a series of novel SIN derivatives was designed and synthesized to improve its anti-inflammatory activity in vitro compared to SIN, and compound 17 significantly inhibited LPS-induced secretion of pro-inflammatory factors NO (IC50 = 30.28 ± 1.70 μM), and suppressed the expression of iNOS, IL-6 and TNF-α in RAW264.7 cells.
Journal ArticleDOI
Synthesis and biological activity evaluation of podophyllotoxin-linked bile acid derivatives as potential anti-liver cancer agents.
Desheng Cai,S-L Andrew Lou,Su Huo,Yu-Qin Yang,Feng Gao,Wenxia Pi,Kedian Chen,Cheng Wang,Xiao-Yan Yang,Jing Jiao,Bing Xu,Penglong Wang,Haimin Lei +12 more
TL;DR: The current research displayed that introduction of bile acids contributed to improve selectivity and activity to cell, and compound 23 could be a promising anti-tumor candidate.
Journal ArticleDOI
Design and Synthesis of Novel Anti-Multidrug-Resistant Staphylococcus Aureus Derivatives of Glycyrrhetinic Acid by Blocking Arginine Biosynthesis, Metabolic and H 2S Biogenesis
Desheng Cai,Xiaoyun Yang,Yu-Qin Yang,Feng Gao,Xue-Hao Cheng,Ya-Juan Zhao,Rui Qi,Yaohua Zhang,Jihui Lu,Xiaoyu Lin,Bing Xu,Penglong Wang,Haimin Lei +12 more
Journal ArticleDOI
Explore bioactive ingredients and potential mechanism of Houpo Mahuang decoction for chronic bronchitis based on UHPLC-Q exactive orbitrap HRMS, network pharmacology, and experiment verification.
Feng Gao,Tong Zhang,Hao Zhang,Ziqi Dai,Yuhao Gu,Min-qiang Lu,Zijie Zhang,Qinling Zeng,Bingxian Shang,Shan Gao,Nianshuang Wang,Bing Xu,Haimin Lei +12 more
TL;DR: In this article , Houpo Mahuang Decoction (HPMHD) has been used for clinical treatment of respiratory diseases for thousands of years and its bioactive ingredients, potential targets and molecular mechanism remain unclear.