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Birgitta Kammandel
Researcher at Max Planck Society
Publications - 4
Citations - 630
Birgitta Kammandel is an academic researcher from Max Planck Society. The author has contributed to research in topics: Enhancer & Regulatory sequence. The author has an hindex of 4, co-authored 4 publications receiving 608 citations.
Papers
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Journal ArticleDOI
Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity.
Birgitta Kammandel,Kamal Chowdhury,Anastassia Stoykova,Samuel Aparicio,Sydney Brenner,Peter Gruss +5 more
TL;DR: A structural and functional conservation of the Pax6 regulatory elements in the vertebrate genome is indicated and Corresponding regulatory elements from pufferfish are able to mimic the reporter expression in transgenic mice.
Journal ArticleDOI
Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6
Martin K. Schwarz,Francesco Cecconi,Gilbert Bernier,Nicole Andrejewski,Birgitta Kammandel,Martin Wagner,Peter Gruss +6 more
TL;DR: A model for Pax gene regulation is proposed that establishes the proper spatial regionalization of the mammalian visual system through reciprocal inhibition of Pax2 promoter/enhancer activity by Pax6 protein and vice versa.
Journal ArticleDOI
Early mesodermal phenotypes in splotch suggest a role for Pax3 in the formation of epithelial somites
Frank Schubert,Patrick Tremblay,Ahmed Mansouri,Anja M. Faisst,Birgitta Kammandel,Andrew Lumsden,Peter Gruss,Susanne Dietrich +7 more
TL;DR: The paired box containing transcription factor Pax3 is a crucial regulator of dermomyotome and muscle development, but the allelic series of Pax3/Splotch mutants also displays characteristic vertebral column malformations, which do not result from defective dorsoventral somite pattern.
Patent
Regulatory sequences involved in pancreas-specific gene expression
Peter Gruss,Birgitta Kammandel +1 more
TL;DR: In this article, uses of the before described recombinant DNA molecules and vectors for the preparation of pharmaceutical compositions for treating, preventing and/or delaying a disease related to the pancreas in a subject are provided.