S
Sydney Brenner
Researcher at Agency for Science, Technology and Research
Publications - 341
Citations - 58033
Sydney Brenner is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Gene & Fugu. The author has an hindex of 95, co-authored 340 publications receiving 54977 citations. Previous affiliations of Sydney Brenner include Bristol Royal Infirmary & Medical Research Council.
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Journal ArticleDOI
The genetics of caenorhabditis elegans
TL;DR: In this paper, the authors describe methods for the isolation, complementation and mapping of mutants of Caenorhabditis elegans, a small free-living nematode worm.
Journal ArticleDOI
The structure of the nervous system of the nematode Caenorhabditis elegans
TL;DR: The structure and connectivity of the nervous system of the nematode Caenorhabditis elegans has been deduced from reconstructions of electron micrographs of serial sections as discussed by the authors.
Journal ArticleDOI
Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays
Sydney Brenner,Maria Johnson,John Bridgham,George Stefan Golda,David H. Lloyd,Davida Johnson,Shujun Luo,Sarah N. McCurdy,Michael F. Foy,Mark Ewan,Rithy Roth,Dave George,Sam Eletr,Glenn Albrecht,Eric Vermaas,Steven Williams,Keith Moon,Timothy Burcham,Michael C. Pallas,Robert B. Dubridge,James W. Kirchner,Karen L. Fearon,Jen-I Mao,Kevin Corcoran +23 more
TL;DR: A novel sequencing approach that combines non-gel-based signature sequencing with in vitro cloning of millions of templates on separate 5 μm diameter microbeads provides an unprecedented depth of analysis permitting application of powerful statistical techniques for discovery of functional relationships among genes.
Journal ArticleDOI
Whole-Genome Shotgun Assembly and Analysis of the Genome of Fugu rubripes
Samuel Aparicio,Jarrod Chapman,Elia Stupka,Nik Putnam,Jer Ming Chia,Paramvir S. Dehal,Alan Christoffels,Sam Rash,Shawn Hoon,Arian F.A. Smit,Maarten D. Sollewijn Gelpke,Jared C. Roach,Tania Oh,Isaac Ho,Marie Wong,Chris Detter,Frans Verhoef,Paul Predki,Alice Tay,Susan Lucas,Paul G. Richardson,Sarah Smith,Melody S. Clark,Yvonne J. K. Edwards,Norman A. Doggett,Andrey Zharkikh,Sean V. Tavtigian,Dmitry Pruss,Mary Barnstead,Cheryl Evans,Holly Baden,Justin Powell,Gustavo Glusman,Lee Rowen,Leroy Hood,Y. H. Tan,Greg Elgar,Trevor Hawkins,Byrappa Venkatesh,Daniel S. Rokhsar,Sydney Brenner +40 more
TL;DR: The Fugu rubripes genome has been sequenced to over 95% coverage, and more than 80% of the assembly is in multigene-sized scaffolds as discussed by the authors.