Role of Streptococcus mutans in human dental decay.

Statistical Methods in Medical Research.

The aim of this study was to develop a valid and reproducible index of orthodontic treatment priority. After reviewing the available literature, it was felt that this could be best achieved by using two separate components to record firstly the dental health and functional indications for treatment, and secondly the aesthetic impairment caused by the malocclusion. A modification of the index used by the Swedish Dental Health Board was used to record the need for orthodontic treatment on dental health and functional grounds. This index was modified by defining five grades, with precise dividing lines between each grade. An illustrated 10-point scale was used to assess independently the aesthetic treatment need of the patients. This scale was constructed using dental photographs of 12-year-olds collected during a large multi-disciplinary survey. Six non-dental judges rated these photographs on a visual analogue scale, and at equal intervals along the judged range, representative photographs were chosen. To test the index in use, two sample populations were defined; a group of patients referred for treatment, and a random sample of 11-12-year-old schoolchildren. Both samples were examined using the index and satisfactory levels of intra- and inter-examiner agreement were obtained.

https://odont.au.dk/fileadmin/www.odontologi.au.dk/afdeling_for_ortodonti/Postgraduate/10_Brook_Shaw_1989_IOTN_evaluation.pdf

The development of an index of orthodontic treatment priority.

https://www.semortho.com/article/S1073-8746(05)00021-6/pdf

The Cervical Vertebral Maturation (CVM) Method for the Assessment of Optimal Treatment Timing in Dentofacial Orthopedics

http://www.endoexperience.com/documents/Cellularmolecularandtissuelevelreactionstoorthoforce_2006.pdf

Cellular, molecular, and tissue-level reactions to orthodontic force

Palatal growth studied on human autopsy material. A histologic microradiographic study.

Orthodontic tooth movement is achieved by (re)modeling processes of the alveolar bone, which are triggered by changes in the stress/strain distribution in the periodontium. In the past, the finite element (FE) method has been used to describe the stressed situation within the periodontal ligament (PDL) and surrounding alveolar bone. The present study sought to determine the impact of the modeling process on the outcome from FE analyses and to relate these findings to the current theories on orthodontic tooth movement. In a series of FE analyses simulating teeth subjected to orthodontic loading, the influence of geometry/morphology, material properties, and boundary conditions was evaluated. The accurate description of alveolar bone morphology and the assignment of non-linear mechanical properties for the PDF elements demonstrate that loading of the periodontium cannot be explained in simple terms of compression and tension along the loading direction. Tension in the alveolar bone was far more predominant than compression.

The Finite Element Method: a Tool to Study Orthodontic Tooth Movement

The healing around an immediately loaded screw was described and related to the bone type, manner of loading and observation time. In four adult macaca fasicularis monkeys, 16 titanium vanadium screws were inserted into the infrazygomatic crest and two in the symphysis region. Immediately after insertion, screws were loaded with 25- and 50-g Sentalloy springs extending to the canines. Following an observation period of 1, 2, 4 and 6 months, the screws and the surrounding bone were removed. Undecalcified serial sections perpendicular to the long axis were made and the degree of osseointegration studied. Two of the screws were lost immediately after insertion. Of the remaining screws, osseointegration was present around all, but two. The integration was independent of bone type, trabecular or cortical, but increased with time. Based on the results of this study, the use of screws described in the report can be recommended as anchorage units in cases where conventional anchorage is not possible.

Immediate loading of implants used for orthodontic anchorage.

A substantial interest exists in developing substitute materials and human recombinant bone-inducing factors to enhance bone regeneration both in the craniofacial complex and in other parts of the skeleton A persistent problem has been to find an animal model that allows for the comparison of different osteopromotive materials The purpose of this investigation was 1) to determine whether a 5-mm calvarial defect in adult rats fulfilled the requirements of a critical-size bone defect and 2) to discuss the use of this animal model in assessing bone repair in the craniofacial region Bilateral full-thickness calvarial defects were trephined in the calvarial bone of 56 5- to 6-month-old Wistar rats Except for minor amounts of bone formation limited to the margins of the defect, none of the defects revealed any signs of spontaneous bone regeneration 6 and 12 months after surgery The full-thickness 5-mm calvarial defects thus fulfill the criteria for a critical-size bone defect This animal model allows for an experiment with a paired design, it avoids inclusion of the sagittal suture in the osseous defect, and it thereby minimizes morbidity by reducing the risk of damaging the midsagittal sinus An adequate experimental model has been developed to evaluate the efficiency of osteopromotive materials in the healing of bone defects in the craniomaxillofacial region

Importance of the critical-size bone defect in testing bone-regenerating materials

Factors of importance for the development of dehiscences during labial movement of mandibular incisors: a retrospective study of adult orthodontic patients.

Birte Melsen

Papers

Palatal growth studied on human autopsy material. A histologic microradiographic study.

The Finite Element Method: a Tool to Study Orthodontic Tooth Movement

Immediate loading of implants used for orthodontic anchorage.

Importance of the critical-size bone defect in testing bone-regenerating materials

Factors of importance for the development of dehiscences during labial movement of mandibular incisors: a retrospective study of adult orthodontic patients.