Biyu Li

TL;DR: Perturb-seq as discussed by the authors combines single-cell RNA sequencing and clustered regularly interspaced short palindromic repeats (CRISPR)-based perturbations to perform many such assays in a pool.

TL;DR: Perturb-seq accurately identifies individual gene targets, gene signatures, and cell states affected by individual perturbations and their genetic interactions, and posit new functions for regulators of differentiation, the anti-viral response, and mitochondrial function during immune activation.

TL;DR: In this article , two pyrenyl Schiff base derivatives with π conjugated structures (B2 and B3) were designed and synthesized, and then they were added into polyurethane to obtain doped and bonded nonlinear optical materials.

TL;DR: In this paper , 4-phenylethylene derivatives (B1, B2 and B3 ) with π conjugated systems were designed and synthesized by Sonogashira coupling reaction and Schiff base reaction.

TL;DR: In this article , two tetrastyryl derivatives (S1, S2) were designed and synthesized by Schiff base reaction and the structure and properties of the compounds were characterized by FT-IR, UV-Vis, TG and Z-scan.