Bo Shopsin

TL;DR: In the NYC collection, spa typing provided a clonal assignment for 185 of 195 strains within the five major groups previously described, and spa sequencing appears to be a highly effective rapid typing tool for S. aureus that, despite some expense of specificity, has significant advantages in terms of speed, ease of use, easy of interpretation, and standardization among laboratories.

TL;DR: It is indicated that while most clinical isolates are haemolytic and agr(+), non-haemolytics and agR(-) strains are found in S. aureus infections, and that agr (+) and agg(-) variants may have a cooperative interaction in certain types of infections.

TL;DR: MRSA colonization is not ubiquitous in persons without predisposing risk outside of the health care environment, and bacterial competition and a lack of strong selection may limit the community spread of MRSA.

TL;DR: In this article, the identification of agr autoinducer receptor specificity groups within a population of Staphylococcus aureus isolates colonizing children and their guardians was performed.

TL;DR: It is demonstrated that leukocidin A/B (LukAB) is required and sufficient for the ability of S. aureus, including MRSA, to kill human neutrophils, macrophages and dendritic cells and underscores LukAB as an important factor that contributes to staphylococcal pathogenesis.