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Boris Polyak
Researcher at Drexel University
Publications - 48
Citations - 2138
Boris Polyak is an academic researcher from Drexel University. The author has contributed to research in topics: Tissue engineering & Population. The author has an hindex of 22, co-authored 47 publications receiving 1910 citations. Previous affiliations of Boris Polyak include Ben-Gurion University of the Negev & Boston Children's Hospital.
Papers
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Journal ArticleDOI
High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents
Boris Polyak,Ilia Fishbein,Michael Chorny,Ivan S. Alferiev,Darryl N. Williams,Ben Yellen,Gary Friedman,Robert J. Levy +7 more
TL;DR: In vivo MNP-loaded BAECs transduced with adenoviruses expressing luciferase (Luc) were targeted to stents deployed in rat carotid arteries in the presence of a uniform magnetic field with significantly greater Luc expression, detected by in vivo optical imaging, than nonmagnetic controls.
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Magnetic targeting for site-specific drug delivery: applications and clinical potential
Boris Polyak,Gary Friedman +1 more
TL;DR: More efficient targeting magnetic systems in combination with prolonged circulation lifespan and carriers' surface recognition properties will improve the targeting efficiency of magnetic nanocarriers and enhance therapeutic agent availability at the molecular site of agent action.
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Magnetic nanoparticle-based approaches to locally target therapy and enhance tissue regeneration in vivo.
TL;DR: This review is focused on drug targeting applications that require penetration of a cellular barrier as well as strategies to improve the efficacy of targeting in these biomedical applications.
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Synthesis and Characterization of a Pyrrole−Alginate Conjugate and Its Application in a Biosensor Construction
TL;DR: N-(3-Aminopropyl)pyrrole was covalently coupled with alginate in an aqueous-phase reaction by means of carbodiimide-mediated activation chemistry to provide a pyrrole-alginate conjugate for subsequent use in biosensor applications.
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Bioluminescent whole cell optical fiber sensor to genotoxicants: system optimization
TL;DR: An Escherichia coli strain, genetically modified to emit a luminescent signal in the presence of genotoxic agents, was alginateimmobilized onto an exposed core of a fiber-optic system, and photon detection efficiency significantly increased, although to a lesser extent than that expected from theoretical calculations.