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Brett E. Fenster
Researcher at St. Joseph Hospital
Publications - 33
Citations - 971
Brett E. Fenster is an academic researcher from St. Joseph Hospital. The author has contributed to research in topics: Pulmonary hypertension & Cardiac magnetic resonance imaging. The author has an hindex of 15, co-authored 33 publications receiving 833 citations. Previous affiliations of Brett E. Fenster include University of Colorado Denver & National Jewish Health.
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Journal ArticleDOI
Novel Role for the Potent Endogenous Inotrope Apelin in Human Cardiac Dysfunction
Mary M. Chen,Euan A. Ashley,David Deng,Anya Tsalenko,Alicia Deng,Raymond Tabibiazar,Amir Ben-Dor,Brett E. Fenster,Eugene Yang,Jennifer Y. King,Michael B. Fowler,Robert C. Robbins,Frances L. Johnson,Laurakay Bruhn,Theresa McDonagh,Henry J. Dargie,Zohar Yakhini,Philip S. Tsao,Thomas Quertermous +18 more
TL;DR: It is demonstrated here using immunoassay and immunohistochemical techniques that apelin is localized primarily in the endothelium of the coronary arteries and is found at a higher concentration in cardiac tissue after mechanical offloading, implying an important paracrine signaling pathway in the heart.
Journal ArticleDOI
Endothelial dysfunction: clinical strategies for treating oxidant stress.
TL;DR: Antioxidants appear to be an attractive candidate therapy, yet despite compelling preclinical evidence supporting their benefits, efforts to validate the use of vitamins C and E in a clinical setting have been conflicting.
Journal ArticleDOI
Galectin-3 levels are associated with right ventricular functional and morphologic changes in pulmonary arterial hypertension.
Brett E. Fenster,Luis Lasalvia,Joyce D. Schroeder,Jamey Smyser,Lori J. Silveira,J. Kern Buckner,Kevin K. Brown +6 more
TL;DR: Serum Gal-3 levels are associated with multiple indices of RV function and morphology, and may represent a novel biomarker for RV remodeling and associated ECM turnover in PAH.
Journal ArticleDOI
Vorticity is a marker of right ventricular diastolic dysfunction
Brett E. Fenster,James Browning,Joyce D. Schroeder,Michal Schäfer,Christopher A Podgorski,Jamey Smyser,Lori J. Silveira,J. Kern Buckner,Jean Hertzberg +8 more
TL;DR: Vorticity may be a robust noninvasive research tool for the investigation of RV fluid and tissue mechanical interactions in PAH and correlates with multiple echocardiographic markers of RVDD.
Journal ArticleDOI
Predictors of Cardiac Sarcoidosis Using Commonly Available Cardiac Studies
Andrew M. Freeman,Douglas Curran-Everett,Howard D. Weinberger,Brett E. Fenster,J. Kern Buckner,E. Bridgette Gottschall,William H. Sauer,Lisa A. Maier,Nabeel Hamzeh +8 more
TL;DR: It is suggested that major findings from screening studies are more likely to correlate with cMRI findings than with findings from FDG-cPET, and major findings were most predictive of positive imaging findings.