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Brian R. Murphy
Researcher at Murphy Oil
Publications - 203
Citations - 15182
Brian R. Murphy is an academic researcher from Murphy Oil. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 70, co-authored 202 publications receiving 14737 citations. Previous affiliations of Brian R. Murphy include California Institute of Technology & Massachusetts Institute of Technology.
Papers
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Journal ArticleDOI
Maximizing multiprocessor performance with the SUIF compiler
Mary Hall,Jennifer M. Anderson,Jennifer M. Anderson,Saman Amarasinghe,Saman Amarasinghe,Brian R. Murphy,Brian R. Murphy,Shih-Wei Liao,Shih-Wei Liao,Edouard Bugnion,Edouard Bugnion,Monica S. Lam,Monica S. Lam,Monica S. Lam +13 more
TL;DR: In this paper, the authors describe automatic parallelization techniques in the SUIF (Stanford University Intermediate Format) compiler that result in good multiprocessor performance for array-based numerical programs.
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Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5' proximal open reading frame of the M2 mRNA in gene expression and provides a capability for vaccine development
TL;DR: It should be possible to introduce defined changes into infectious RSV using the M2(ORF1) protein, consistent with its recent identification as a transcription elongation factor and confirms its importance for RSV gene expression.
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Serum and nasal wash antibodies associated with resistance to experimental challenge with influenza A wild-type virus.
TL;DR: Observations suggest that live vaccine virus infection-induced and inactivated vaccine-induced immunity may involve different compartments of the immune system; sufficient antibody in either serum or nasal secretions is capable of conferring resistance.
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Immune Response to Dengue Virus and Prospects for a Vaccine
TL;DR: Vaccines will need to provide long-term protection against each of the four DENV serotypes by inducing neutralizing antibodies, and live, attenuated and various nonliving virus vaccines are in development.
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Prior Infection and Passive Transfer of Neutralizing Antibody Prevent Replication of Severe Acute Respiratory Syndrome Coronavirus in the Respiratory Tract of Mice
Kanta Subbarao,Josephine M. McAuliffe,Leatrice Vogel,Gary A. Fahle,Steven H. Fischer,Kathleen M. Tatti,Michelle M. Packard,Wun-Ju Shieh,Sherif R. Zaki,Brian R. Murphy +9 more
TL;DR: In this article, passive transfer of immune serum to naive mice prevented virus replication in the lower respiratory tract following intranasal challenge, which is a promising observation for the development of vaccines, immunotherapy, and immunoprophylaxis regimens.