B
Brigitte Eibl
Researcher at University of Innsbruck
Publications - 18
Citations - 1981
Brigitte Eibl is an academic researcher from University of Innsbruck. The author has contributed to research in topics: Cytotoxic T cell & Bone marrow. The author has an hindex of 13, co-authored 18 publications receiving 1958 citations.
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Journal ArticleDOI
Generation of mature dendritic cells from human blood An improved method with special regard to clinical applicability
Nikolaus Romani,Daniela Reider,Marion Heuer,Susanne Ebner,Eckhart Kämpgen,Brigitte Eibl,Dietger Niederwieser,Gerold Schuler +7 more
TL;DR: The method is adapted to consider several variables that are pertinent to clinical use, including a change from fetal calf serum to human plasma and to media approved for clinical use like X-VIVO or AIM-V.
Journal ArticleDOI
Evidence for a graft-versus-tumor effect in a patient treated with marrow ablative chemotherapy and allogeneic bone marrow transplantation for breast cancer
Brigitte Eibl,Hubert Schwaighofer,David Nachbaur,Christian Marth,Anne Gächter,R. Knapp,Günther Böck,Christoph Gassner,Lothar Schiller,Finn Petersen,Dietger Niederwieser +10 more
TL;DR: Clinical course and in vitro results suggest that a graft-versus-tumor (GvT) effect might exist after allogeneic BMT for breast cancer, however, clinical experience on a larger scale would be required to determine the clinical efficacy of GvT effects in patients with solid tumors.
Journal ArticleDOI
Dendritic cells generated from blood precursors of chronic myelogenous leukemia patients carry the philadelphia translocation and can induce a CML‐specific primary cytotoxic T‐cell response
Brigitte Eibl,Susanne Ebner,Christoph Duba,Günther Böck,Nikolaus Romani,Martin Erdel,Anne Gächter,Dietger Niederwieser,Gerold Schuler,Gerold Schuler +9 more
TL;DR: It is concluded that DC can be generated from blood progenitors of CML patients in vitro and exhibit, to a large extent, the Philadelphia (Ph) translocation.
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LST1: a gene with extensive alternative splicing and immunomodulatory function.
Ingrid Rollinger-Holzinger,Brigitte Eibl,Marc Pauly,Ute Griesser,François Hentges,Bernhard Auer,Georg Pall,Peter Schratzberger,Dietger Niederwieser,Elisabeth H. Weiss,Heinz Zwierzina +10 more
TL;DR: The data demonstrate the protein expression of LST1 on the cell surface of mononuclear cells, and they show an inhibitory effect on lymphocyte proliferation of two L ST1 proteins although they have only a very short amino acid homology.
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Immune response modulation by pentoxifylline in vitro
Herbert Tilg,Brigitte Eibl,Marion Pichl,Anne Gächter,Manfred Herold,Juliana Brankova,Christoph Huber,Dietger Niederwieser +7 more
TL;DR: PTX has profound immunomodulatory properties in vitro, which are associated with selective inhibition of cytokine release and can be enhanced by the addition of mAbs against TNF-α, but not reversed by the added of rTNF- α.