Bruce S. Shapiro

TL;DR: The clinical pregnancy rate per transfer was significantly greater in the cryopreservation group than in the fresh group, which strongly suggest impaired endometrial receptivity in fresh ET cycles after ovarian stimulation, when compared with FET cycles with artificialendometrial preparation.

TL;DR: There have been reports of greater implantation and pregnancy rates with FET than with fresh autologous embryo transfer, suggesting superior endometrial receptivity in the absence of ovarian stimulation.

TL;DR: Quantitative measurements of the inner cell mass are highly indicative of blastocyst implantation potential and Blastocysts with relatively large and/or slightly oval ICMs are more likely to implant than other blastocysts.

TL;DR: The superior PRs with day 5 blastocyst transfers in fresh autologous cycles and with day 6 blastocysts in donor cycles may have resulted from better synchrony with endometrial development, which was further supported by the superior performance of day 6blastocyst in FET cycles relative to their fresh counterparts.

TL;DR: Embryos that develop to the expanded blastocyst stage and are transferred on day 5 after retrieval are approximately twice as likely to implant compared to those for which expansion and transfer are delayed until day 6.