B
Brun H. Mietzner
Researcher at University of Jena
Publications - 2
Citations - 344
Brun H. Mietzner is an academic researcher from University of Jena. The author has contributed to research in topics: Phosphorylation & Frataxin. The author has an hindex of 2, co-authored 2 publications receiving 330 citations.
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Journal ArticleDOI
Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisited.
Tim J. Schulz,René Thierbach,Anja Voigt,Gunnar Drewes,Brun H. Mietzner,Pablo Steinberg,Andreas Pfeiffer,Michael Ristow,Michael Ristow +8 more
TL;DR: The view that an increase in oxidative metabolism induced by mitochondrial frataxin may inhibit cancer growth in mammals is supported.
Journal ArticleDOI
Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice.
René Thierbach,Tim J. Schulz,Frank Isken,Aanja Voigt,Brun H. Mietzner,Gunnar Drewes,Jürgen-Christoph von Kleist-Retzow,Rudolf J. Wiesner,Mark A. Magnuson,Hélène Puccio,Andreas Pfeiffer,Pablo Steinberg,Michael Ristow +12 more
TL;DR: Findings indicate that frataxin may act as a mitochondrial tumor suppressor protein in mammals by promoting both apoptosis and proliferation in murine hepatocytes.