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Bruno Brochet

Researcher at French Institute of Health and Medical Research

Publications -  65
Citations -  2252

Bruno Brochet is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Multiple sclerosis & Cognition. The author has an hindex of 23, co-authored 65 publications receiving 2048 citations.

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Journal Article

MR Imaging of Relapsing Multiple Sclerosis Patients Using Ultra-Small-Particle Iron Oxide and Compared with Gadolinium

TL;DR: In this article, a prospective MR imaging study of 10 patients with MS in acute relapses was achieved by using ultra-smallparticle iron oxide (USPIO) and gadolinium.

ORIGINAL RESEARCH MR Imaging of Relapsing Multiple Sclerosis Patients Using Ultra-Small-Particle Iron Oxide and Compared with Gadolinium

TL;DR: The visualization of macrophage activity in vivo with USPIO characterize a distinct cellular and inflammatory event of the dynamic process of MS lesion formation, complementary to the increased BBB permeability seen with gadolinium.
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Primary and transitional progressive MS: a clinical and MRI cross-sectional study.

TL;DR: The monitoring of disease progression in PPMS is difficult, although measures of atrophy correlate with the EDSS and appear most promising, which increases the understanding of this unique patient group, which will be further expanded with the acquisition of serial data.
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How to detect cognitive dysfunction at early stages of multiple sclerosis

TL;DR: Since, at this stage, patients’ cognitive complaints are already influenced by depression and fatigue and do not accurately reflect cognitive performances, the SDMT may help to select patients for testing with a more complete cognitive battery.
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Unexpected multiple sclerosis: follow-up of 30 patients with magnetic resonance imaging and clinical conversion profile

TL;DR: A descriptive retrospective study of clinical and 5 year MRI follow-up in patients with subclinical demyelinating lesions fulfilling MRI Barkhof–Tintoré criteria with a normal neurological examination, which is the first cohort of CIS with preclinical follow- up.