P
Pierre Labauge
Researcher at University of Montpellier
Publications - 431
Citations - 13775
Pierre Labauge is an academic researcher from University of Montpellier. The author has contributed to research in topics: Multiple sclerosis & Medicine. The author has an hindex of 56, co-authored 390 publications receiving 11424 citations. Previous affiliations of Pierre Labauge include French Institute of Health and Medical Research & Paris Diderot University.
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Journal ArticleDOI
Truncating mutations in CCM1, encoding KRIT1, cause hereditary cavernous angiomas.
S Laberge-le Couteulx,H H Jung,Pierre Labauge,J.P. Houtteville,Christelle Lescoat,Michaelle Cecillon,Emmanuelle Maréchal,Anne Joutel,Jean Francois Bach,E. Tournier-Lasserve +9 more
TL;DR: The data suggest the involvement of the RAP1A signal transduction pathway in vasculogenesis or angiogenesis in Cavernous angiomas families, and that CCM1, a gene whose protein product, KRIT1, interacts with R AP1A (also known as KREV1; ref. 9), a member of theRAS family of GTPases, is mutated inCCM1 families.
Journal ArticleDOI
OPA1 mutations induce mitochondrial DNA instability and optic atrophy plus phenotypes
Patrizia Amati-Bonneau,Maria Lucia Valentino,Pascal Reynier,María Esther Gallardo,Belén Bornstein,Anne Boissiere,Yolanda Campos,Henry Rivera,Jesús González de la Aleja,Rosanna Carroccia,Luisa Iommarini,Pierre Labauge,Dominique Figarella-Branger,Pascale Marcorelles,Alain Furby,Katell Beauvais,Franck Letournel,Rocco Liguori,Chiara La Morgia,Pasquale Montagna,Maria Liguori,Claudia Zanna,Michela Rugolo,Andrea Cossarizza,Bernd Wissinger,Christophe Verny,Robert Schwarzenbacher,Miguel A. Martín,Joaquiotan Arenas,Carmen Ayuso,Rafael Garesse,Guy Lenaers,Dominique Bonneau,Valerio Carelli +33 more
TL;DR: In this paper, mutations in the OPA1 gene can also be responsible for a syndromic form of DOA associated with sensorineural deafness, ataxia, axonal sensory-motor polyneuropathy, chronic progressive external ophthalmoplegia and mitochondrial myopathy.
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Mutations within the Programmed Cell Death 10 Gene Cause Cerebral Cavernous Malformations
Françoise Bergametti,Christian Denier,Pierre Labauge,Minh Arnoult,S. Boetto,Michel Clanet,P. Coubes,B. Echenne,Rony Ibrahim,B. Irthum,G. Jacquet,M. Lonjon,Jean Jacques Moreau,J.P. Neau,Fabrice Parker,M. Tremoulet,E. Tournier-Lasserve +16 more
TL;DR: The identification of PDCD10 (programmed cell death 10) as the CCM3 gene strongly suggests that it is a new player in vascular morphogenesis and/or remodeling in cerebral cavernous malformations.
Journal ArticleDOI
A gene for familial hemiplegic migraine maps to chromosome 19.
Anne Joutel,Marie-Germaine Bousser,Valérie Biousse,Pierre Labauge,Hugues Chabriat,Argentino Nibbio,Jacqueline Maciazek,Bénédicte Meyer,Marie-Anne Bach,Jean Weissenbach,G. Mark Lathrop,Elisabeth Tournier-Lasserve +11 more
TL;DR: Multilocus linkage analysis suggested that the loci responsible for the two diseases reside within an interval of about 30 cM on chromosome 19.
Journal ArticleDOI
Clinical Characteristics and Outcomes in Patients With Coronavirus Disease 2019 and Multiple Sclerosis.
Céline Louapre,Nicolas Collongues,B. Stankoff,C. Giannesini,Caroline Papeix,C. Bensa,Romain Deschamps,Alain Créange,Abir Wahab,Jean Pelletier,Olivier Heinzlef,Pierre Labauge,Laurent Guilloton,Guido Ahle,Mathilde Goudot,Kévin Bigaut,David Laplaud,Sandra Vukusic,Catherine Lubetzki,Jérôme De Seze +19 more
TL;DR: In this registry-based cohort study of patients with MS, age, EDSS, and obesity were independent risk factors for severe COVID-19; there was no association found between DMTs exposure and CO VID-19 severity.