Bruno Luan Mello

TL;DR: It is demonstrated that binding of CBMs to cellulose is non-homogeneous, irreversible and leads to its amorphisation, and effects of CBM-promoted amorphogenesis on cellulose hydrolysis by cellulases are revealed.

TL;DR: This approach provides evidence that factors such as nutrient availability has a significant selective pressure on the biodiversity of microorganisms in MCs and nutrient-limited medium may displace bacterial generalist species, leading to an enriched source for mining novel enzymes for biotechnology applications.

TL;DR: The structural studies and molecular dynamics simulations show that the flexibility of Tyr260, in comparison with Tyr247 from the homologous Trichoderma reesei Cel7A, is enhanced as a result of the short side‐chains of adjacent Val216 and Ala384 residues and creates an additional gap at the side face of the catalytic tunnel.

TL;DR: This study demonstrated that composting microbiomes continue to be an excellent source of biotechnologically important enzymes by unveiling the diversity of enzymes involved in in situ lignocellulose degradation.

TL;DR: It is demonstrated that family 1 carbohydrate-binding modules are able to potentiate the enzymatic degradation of the polysaccharides and their application might contribute to diminishing the currently prohibitive costs of the lignocellulose saccharification process.