L
Larissa C. Textor
Researcher at University of São Paulo
Publications - 7
Citations - 124
Larissa C. Textor is an academic researcher from University of São Paulo. The author has contributed to research in topics: Trichoderma harzianum & Cellulase. The author has an hindex of 5, co-authored 7 publications receiving 105 citations. Previous affiliations of Larissa C. Textor include International Federation of Sport Climbing.
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Journal ArticleDOI
Joint X-ray crystallographic and molecular dynamics study of cellobiohydrolase I from Trichoderma harzianum: deciphering the structural features of cellobiohydrolase catalytic activity.
Larissa C. Textor,Francieli Colussi,Rodrigo Lanna Franco da Silveira,Viviane Isabel Serpa,Bruno Luan Mello,João R. C. Muniz,Fabio M. Squina,Nei Pereira,Munir S. Skaf,Igor Polikarpov +9 more
TL;DR: The structural studies and molecular dynamics simulations show that the flexibility of Tyr260, in comparison with Tyr247 from the homologous Trichoderma reesei Cel7A, is enhanced as a result of the short side‐chains of adjacent Val216 and Ala384 residues and creates an additional gap at the side face of the catalytic tunnel.
Journal ArticleDOI
An alternative conformation of ERβ bound to estradiol reveals H12 in a stable antagonist position
Paulo C. T. Souza,Paulo C. T. Souza,Larissa C. Textor,Denise C. Melo,Alessandro S. Nascimento,Munir S. Skaf,Igor Polikarpov +6 more
TL;DR: Structural observations and molecular dynamics simulations jointly provide evidence that alternative ERβ H12 position could correspond to a stable conformation of the receptor under physiological pH conditions and shed light on the unexpected role of LBD in the lower functional response of ERβ subtype.
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Crystal Structure Analysis of Peroxidase from the Palm Tree Chamaerops Excelsa.
Amanda Bernardes,Larissa C. Textor,Jademilson C. Santos,Nazaret Hidalgo Cuadrado,Eduard Y. Kostetsky,Manuel G. Roig,Vassiliy N. Bavro,João R. C. Muniz,Valery L. Shnyrov,Igor Polikarpov +9 more
TL;DR: It is demonstrated, that this dimeric arrangement results in a more stable protein quaternary structure through stabilization of the regions that are highly dynamic in other peroxidases.
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Sets of Covariant Residues Modulate the Activity and Thermal Stability of GH1 β-Glucosidases
TL;DR: Nine covariant positions seem to jointly modulate the thermal stability of β-glucosidases, which modulates their catalytic activity and substrate specificity via direct contact with the active site residues.
Journal ArticleDOI
Purification, crystallization and preliminary crystallographic analysis of the catalytic domain of the extracellular cellulase CBHI from Trichoderma harzianum
Francieli Colussi,Larissa C. Textor,Viviane Isabel Serpa,Roberto Nobuyuki Maeda,Nei Pereira,Igor Polikarpov +5 more
TL;DR: The filamentous fungus Trichoderma harzianum has a considerable cellulolytic activity that is mediated by a complex of enzymes which are essential for the hydrolysis of microcrystalline cellulose and the catalytic core domain of cellobiohydrolase I was purified from the extracellular extracts and submitted to robotic crystallization.