B
Bruno Lucas
Researcher at University of Limoges
Publications - 136
Citations - 3015
Bruno Lucas is an academic researcher from University of Limoges. The author has contributed to research in topics: T cell & Seebeck coefficient. The author has an hindex of 27, co-authored 131 publications receiving 2706 citations. Previous affiliations of Bruno Lucas include University of Paris-Sud & University of Paris.
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Journal Article
Cell expansion and growth arrest phases during the transition from precursor (CD4-8-) to immature (CD4+8+) thymocytes in normal and genetically modified mice.
TL;DR: The kinetics and cell size evolution suggest that the majority of these cells do not give rise to CD4+CD8+ cells, and in RAG-2-/- cells, the block at the CD44-CD25high stage involved all cells.
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Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells.
Ying Wang,Adrien Kissenpfennig,Michael Mingueneau,Sylvie Richelme,Pierre Perrin,Stéphane Chevrier,Céline Genton,Bruno Lucas,James P. DiSanto,Hans Acha-Orbea,Bernard Malissen,Marie Malissen +11 more
TL;DR: The results argue against a scenario where the LatY136F pathology is primarily due to a lack of functional Foxp3+ regulatory T cells and suggest that a defect intrinsic to Laty136F CD4 T cells leads to a state of TCR-independent hyperactivity.
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Naive T cells proliferate strongly in neonatal mice in response to self-peptide/self-MHC complexes
Armelle Le Campion,Christine Bourgeois,Florence Lambolez,Bruno Martin,Sandrine Léaument,Nicole Dautigny,Corinne Tanchot,Claude Penit,Bruno Lucas +8 more
TL;DR: It is demonstrated that the proliferation of the first thymic emigrants reaching the periphery requires T cell antigen receptor-self-peptide/self-MHC interactions and is regulated by the size of the peripheral T cell pool.
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Peripheral CD8+CD25+ T lymphocytes from MHC class II-deficient mice exhibit regulatory activity.
TL;DR: It is shown that CD8+ T cells constitutively expressing CD25 in mice lacking the expression of MHC class II molecules are present not only in the periphery but also in the thymus, and these cells share phenotypic and functional features with regulatory CD4+CD25- T cells.
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Organic transistors and phototransistors based on small molecules
TL;DR: In this paper, a review of recently synthesized p- or n-type organic semiconductors, particularly those suitable for fabrication of solution-processed and/or air-stable field effect transistors with an emphasis on low-cost wet processes, is presented.