B
Bruno Silva
Researcher at University of Coimbra
Publications - 21
Citations - 1002
Bruno Silva is an academic researcher from University of Coimbra. The author has contributed to research in topics: Hypericum perforatum & Subventricular zone. The author has an hindex of 9, co-authored 19 publications receiving 915 citations. Previous affiliations of Bruno Silva include University of Minho.
Papers
More filters
Journal ArticleDOI
Phytochemical and antioxidant characterization of Hypericum perforatum alcoholic extracts
TL;DR: The antioxidant potentials of a total ethanolic extract of Hypericum perforatum (TE) and fractions were evaluated and correlated with their phenolic contents in this article, and the extracts were fully characterised by HPLC-DAD-MS-MS.
Journal ArticleDOI
Tumor Necrosis Factor‐α Modulates Survival, Proliferation, and Neuronal Differentiation in Neonatal Subventricular Zone Cell Cultures
TL;DR: Results show that TNF‐α induces neurogenesis in neonatal SVZ cell cultures of mice, a proinflammatory cytokine and a proneurogenic factor, that may play a central role in promoting neuroGenesis and brain repair in response to brain injury and infection.
Journal ArticleDOI
Neuropeptide Y promotes neurogenesis in murine subventricular zone.
Fabienne Agasse,Liliana Bernardino,Heidi Kristiansen,Søren H. Christiansen,Raquel Ferreira,Bruno Silva,Sofia Grade,David P.D. Woldbye,João O. Malva +8 more
TL;DR: NPY, as a promoter of SVZ neurogenesis, is a crucial factor for future development of cell‐based brain therapy and may be useful for the stimulation of SVz dynamic in brain repair purposes.
Journal ArticleDOI
St. John’s Wort (Hypericum perforatum) extracts and isolated phenolic compounds are effective antioxidants in several in vitro models of oxidative stress
TL;DR: In this article, the antioxidant potential of a total ethanolic extract of Hypericum perforatum (TE) was assessed, and correlated with the phenolic composition of the extract.
Journal ArticleDOI
Quercetin, kaempferol and biapigenin from Hypericum perforatum are neuroprotective against excitotoxic insults.
TL;DR: The results suggest that the neuroprotective action induced by quercetin and kaempferol are mainly mediated by antioxidant effects, whereas biapigenin mainly affects mitochondrial bioenergetics and calcium uptake.