The structural chemistry of metal thiolate complexes

The Chemistry of Transition Metal Complexes Containing Catechol and Semiquinone Ligands

Structural survey of technetium complexes

Medical Diagnostic Imaging with Complexes of 99mTc

Technetium Chemistry and Technetium Radiopharmaceuticals

Preparation and crystal structure of tetraphenylarsonium bis(2-mercaptoethanolato)oxotechnetate

Synthesis and characterization of complexes containing the bis(1, 2-diolato)-oxotechnetium(V) core

The complexes (Bu 4 N)[TcO(O 2 C 6 H 4 ) 2 ] ( 1 ) and Na[TcO(OCH 2 CH 2 O) 2 ] ( 2 ) have been prepared by reacting TcOCl 4 - with respective diols in methanol. Compound 2 was identified by its elemental analysis and field desorption mass spectrum. Crystals of compound 1 are monoclinic, C 2/ c , with cell dimensions a = 10.393(3), b = 13.835(3), c = 20.643(5) A, β = 101.74(3)° and four formula units in the unit cell. The crystal structure was determined by standard methods and refined to R 1 = 0.0694, R 2 = 0.0613, on the basis of 2887 independent reflections. The data were collected with use of Mo Kα radiation and a Syntex P 2 1 diffractometer. The anion of 1 is square pyramidal with a short TcO(oxo) bond (1.648(5) A). TcO distances to the diolate groups are longer (1.956(3), 1.958(3) A). The technetium atom lies 0.7014(4) A out of the plane of the four diolate oxygen atoms. Compound 2 is hydrolytically unstable in pure water, but can be stabilized by the addition of a several-fold molar excess of ethylene glycol. Compound 1 decomposes minimally in pure water after 24 h. These complexes are shown to be good structural models for 99m Tc-radiopharmaceuticals containing purely oxygen-donor ligands. Comparison of the physical properties of the structurally characterized members of the series of complexes with core structures TcOS x O (4- x ) ( x = O, 2, 4) shows a shift to low energy in the frequency of the terminal oxygen-technetium band in the IR correlated with increasing softness of the basal plane donor atom set.

Bruno V. DePamphilis

Papers

Preparation and crystal structure of tetraphenylarsonium bis(2-mercaptoethanolato)oxotechnetate

Synthesis and characterization of complexes containing the bis(1, 2-diolato)-oxotechnetium(V) core

Preparation and crystal structure of tetraphenylarsonium bis(2-mercaptoethanolato)oxotechnetate

Synthesis and Characterization of Complexes Containing the Bis(1,2-diolato)oxotechnetium(V) Core.