Showing papers by "Byron L. Lam published in 2007"
TL;DR: Patients with unilateral NAION are at a significantly higher risk of developing NAION in the fellow eye after CE, according to a Cox proportional hazards regression model of NAION incidence in theellow eye.
Abstract: Aim: To determine the risk of non-arteritic anterior ischaemic optic neuropathy (NAION) after cataract extraction (CE) in the fellow eye of patients with prior unilateral NAION. Design: Retrospective, cohort study. Methods: Medical records of patients with NAION evaluated in our institution between 1 January 1986 and 31 December 2001 were reviewed to determine the onset of NAION and the time of CE. Patients were excluded if the date of NAION and CE was unreliable, or if CE in the fellow eye was performed before the unilateral NAION. Statistical analysis was performed by including fellow eye CE as a time-dependent covariate in a Cox proportional hazards regression model of NAION incidence in the fellow eye. Results: Of the 325 eligible patients, 9 (53%) of 17 patients with NAION who underwent CE in the fellow eye developed fellow eye NAION, and 59 (19%) of 308 patients with NAION who did not undergo CE in the fellow eye developed fellow eye NAION. Cataract extraction in the fellow eye increased the risk of NAION occurrence in the fellow eye by 3.6-fold (Cox regression, p = 0.001). Conclusions: Patients with unilateral NAION are at a significantly higher risk of developing NAION in the fellow eye after CE.
47 citations
TL;DR: In this paper, visual impairment and hearing impairment are independent predictors of reduced survival in selected studies of community-residing adults, and the association of visual impairment with reduced survival was investigated.
Abstract: Purpose: Visual impairment and, to a lesser extent, hearing impairment are independent predictors of reduced survival in selected studies of community-residing adults. To date, the association of s...
32 citations
TL;DR: Mild enhanced s-cone syndrome (ESCS) associated with a novel heterozygous mutation of the NR2E3 gene is reported associated with modestly impaired ESCS ERG results.
32 citations
TL;DR: Although GCA has been reported to be rare in Hispanics, it was found the prevalence and clinical course of GCA to be similar in Hispanic and non-Hispanic patients.
31 citations
TL;DR: Patients with unilateral NAION are at a significantly higher risk of developing NAION in the fellow eye after CE, according to a Cox proportional hazards regression model of fellow eye NAION incidence.
Abstract: Background/Aims: To determine the risk of non-
arteritic anterior ischemic optic neuropathy (NAION)
after cataract extraction (CE) in the fellow eye of
patients with prior unilateral NAION. Design: Retrospective, cohort study.
Methods: Medical records of patients with NAION
evaluated in our institution between January 1, 1986 and
December 31, 2001 were reviewed to determine the onset
of NAION and the time of CE. Cases were excluded if the
date of NAION and CE was unreliable or if fellow eye CE
was performed before the unilateral NAION. Statistical
analysis was performed by including fellow eye CE as a
time dependent covariate in a Cox proportional hazards
regression model of fellow eye NAION incidence.
Results: Of the 325 eligible patients, 9 (53%) of
17 NAION patients who underwent CE in the fellow eye
developed fellow eye NAION, and 59 (19%) of 308 NAION
patients who did not undergo CE in the fellow eye
developed fellow eye NAION. Cataract extraction in the
fellow eye increased the risk of NAION occurrence in the
fellow eye by 3.6 times (Cox regression, p=0.001).
Conclusions: Patients with unilateral NAION are
at a significantly higher risk of developing NAION in
the fellow eye after CE.
8 citations