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C. Brian Fitzgerald
Researcher at University College Cork
Publications - 3
Citations - 267
C. Brian Fitzgerald is an academic researcher from University College Cork. The author has contributed to research in topics: Bacteriophage & Lysogenic cycle. The author has an hindex of 2, co-authored 3 publications receiving 176 citations.
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Journal ArticleDOI
ΦCrAss001 represents the most abundant bacteriophage family in the human gut and infects Bacteroides intestinalis.
Andrey N. Shkoporov,Ekaterina V. Khokhlova,C. Brian Fitzgerald,Stephen R. Stockdale,Lorraine A. Draper,R. Paul Ross,R. Paul Ross,Colin Hill +7 more
TL;DR: Bacteriophages of the crAssphage family have not yet been isolated in culture and it is shown that it infects the human gut symbiont Bacteroides intestinalis, confirming previous in silico predictions of the likely host.
Journal ArticleDOI
Probing the "Dark Matter" of the Human Gut Phageome: Culture Assisted Metagenomics Enables Rapid Discovery and Host-Linking for Novel Bacteriophages
C. Brian Fitzgerald,Andrey N. Shkoporov,Aditya Upadrasta,Ekaterina V. Khokhlova,R. Paul Ross,Colin Hill +5 more
TL;DR: In this article, a method that enables rapid discovery and host-linking of novel bacteriophages in the gut via a combination of serial enrichment cultures and shotgun metagenomics of viral DNA was described.
Posted ContentDOI
ΦCrAss001, a member of the most abundant bacteriophage family in the human gut, infects Bacteroides
Andrey N. Shkoporov,Ekaterina V. Khokhlova,C. Brian Fitzgerald,Stockdale,Lorraine A. Draper,R. Paul Ross,Colin Hill +6 more
TL;DR: Genome analysis demonstrated that the phage DNA is 102 kb in size, has an unusual genome organisation and does not possess any obvious genes for lysogeny, and electron microscopy confirms that φcrAss001 has a podovirus-like morphology.