C
C. F. Alves
Researcher at Universidade Federal de Minas Gerais
Publications - 6
Citations - 256
C. F. Alves is an academic researcher from Universidade Federal de Minas Gerais. The author has contributed to research in topics: Trypanosoma cruzi & Visceral leishmaniasis. The author has an hindex of 6, co-authored 6 publications receiving 241 citations. Previous affiliations of C. F. Alves include Universidade Federal de Ouro Preto.
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Journal ArticleDOI
Expression of IFN-γ, TNF-α, IL-10 and TGF-β in lymph nodes associates with parasite load and clinical form of disease in dogs naturally infected with Leishmania (Leishmania) chagasi
Cíntia F. Alves,Izabela Ferreira Gontijo de Amorim,Eliane Perlatto Moura,Raul Rio Ribeiro,C. F. Alves,Marilene Suzan Marques Michalick,Evanguedes Kalapothakis,Oscar Bruna-Romero,Wagner Luiz Tafuri,Mauro M. Teixeira,Maria Norma Melo +10 more
TL;DR: The balance of expression of IFN-gamma and TNF-alpha (protective) and IL-10 and TGF-beta (disease progression) in lymph nodes determine parasite burden and clinical expression in naturally infected dogs.
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Effects of specific treatment on parasitological and histopathological parameters in mice infected with different Trypanosoma cruzi clonal genotypes
Max Jean de Ornelas Toledo,Maria Terezinha Bahia,Vanja Maria Veloso,Cláudia Martins Carneiro,George Luiz Lins Machado-Coelho,C. F. Alves,Helen Rodrigues Martins,Ruth Elizabeth Cruz,Washington Luiz Tafuri,Marta de Lana +9 more
TL;DR: The results indicate that phylogenetic divergence among T. cruzi clonal genotypes must be taken in account in chemotherapy and studies dealing with all aspects of the parasite and the disease.
Journal ArticleDOI
American Tegumentary Leishmaniasis: Effectiveness of an Immunohistochemical Protocol for the Detection of Leishmania in Skin
C. F. Alves,Cíntia F. Alves,Maria Marta Figueiredo,Carolina Carvalho de Souza,George Luiz Lins Machado-Coelho,Maria Norma Melo,Washington Luiz Tafuri,Pedro Raso,Rodrigo Pedro Soares,Wagner Luiz Tafuri +9 more
TL;DR: The data are encouraging with regard to validating IHC as a standard alternative method for ATL diagnosis, and the polymer-based technology is less time-consuming and labor intensive than the IHC labeled streptavidin-biotin peroxidase method.
Journal ArticleDOI
Humoral immunological profile and parasitological statuses of Leishmune vaccinated and visceral leishmaniasis infected dogs from an endemic area.
I.F.G. de Amorim,Eloísa de Freitas,C. F. Alves,W.L. Tafuri,Melo Mn,M. S. M. Michalick,A.P. da Costa-Val +6 more
TL;DR: A comparison of the humoral immunological profiles of both groups using Leishmania soluble antigen (LSA) and fucose-mannose ligand shows that Leishmune-immunised animals and VL naturally infected dogs present different Immunological profiles, even though these differences cannot be used to distinguish between these two groups of dogs.
Journal ArticleDOI
Influence of the long-term Trypanosoma cruzi infection in vertebrate host on the genetic and biological diversity of the parasite.
Vanja Maria Veloso,Alvaro J. Romanha,Marta de Lana,Silvane M. F. Murta,Cláudia Martins Carneiro,C. F. Alves,C. F. Alves,E. C. Borges,Washington Luiz Tafuri,George Luiz Lins Machado-Coelho,Egler Chiari,M. T. Bahia +11 more
TL;DR: The findings confirmed the population heterogeneity of the Be-78 strain, and showed how differently it responds to the long-term infection in the same vertebrate hosts, as well as identifying two distinct genetic groups of parasites.