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C. P. A. T. Klein
Researcher at Leiden University
Publications - 55
Citations - 4585
C. P. A. T. Klein is an academic researcher from Leiden University. The author has contributed to research in topics: Hydroxylapatite & Calcium. The author has an hindex of 28, co-authored 55 publications receiving 4479 citations. Previous affiliations of C. P. A. T. Klein include University of Amsterdam & Academic Center for Dentistry Amsterdam.
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Plasma sprayed coatings of hydroxylapatite
TL;DR: The technique of plasma spraying has been applied to deposit a thin, dense layer of hydroxylapatite onto a titanium substrate, and animal studies showed similar histological reactions to apatite coatings as to (well documented) Apatite bulk materials.
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Bonding of bone to apatite-coated implants
TL;DR: Results indicate that apatite-coated implants can form a chemical fixation with a strength comparable to that of cortical bone itself, far stronger than that provided by current cemented or uncemented fixation techniques.
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A histological and histomorphometrical investigation of fluorapatite, magnesiumwhitlockite, and hydroxylapatite plasma-sprayed coatings in goats.
Wouter J.A. Dhert,C. P. A. T. Klein,John A. Jansen,E. A. van der Velde,R. C. Vriesde,P. M. Rozing,K. de Groot +6 more
TL;DR: The results demonstrated that FA showed a high amount of bone apposition without signs of degradation or dissolution, and HA showed considerable reduction in thickness and at 12 weeks an adverse tissue reaction, however, at 25 weeks the amount ofBone apposition was significantly increased compared with the 12-week implants.
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In vivo study of calcium phosphate cements: implantation of an α-tricalcium phosphate/dicalcium phosphate dibasic/tetracalcium phosphate monoxide cement paste
TL;DR: The cement is a promising material as a bone substitute; however, there is a problem of migration while setting in soft tissue and of exclusion from the bone defects by intense bleeding.
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Studies of the solubility of different calcium phosphate ceramic particles in vitro.
C. P. A. T. Klein,C. P. A. T. Klein,J.M.A de Blieck-Hogemrst,J.G.C. Wolket,K. de Groot,K. de Groot +5 more
TL;DR: In vitro solubility tests of hydroxyapatite, tetracalcium phosphate or tricalcium phosphate particles were performed in lactate, citrate, Gomoris or Michaelis buffer with pH 6.2 or 7.2 and in aqua destillata and the results showed that in general thesolubility decreased, except for lactate or citrate buffer, which had a rather stable pH value.