Showing papers in "Biomaterials in 1997"

TL;DR: A review of the literature on the reaction of cells to their surrounding topography and a summary of the types of prosthesis where advantage has been taken of the ability to fabricate topography.

TL;DR: An experimental investigation was undertaken to measure the intrinsic elastic properties of several of the microstructural components of human vertebral trabecular bone and tibial cortical bone by the nanoindentation method, and differences in the measured moduli are statistically significant.

TL;DR: In vitro and in vivo degradations of these films occurred less rapidly without passing a maximum or minimum, as their degree of deacetylation became higher, since both chitin and chitosan are crystalline polymers.

TL;DR: It appears that alginate sponges may provide an excellent support for cell transplantation and be suitable for cell culture and neovascularization.

TL;DR: It would appear that ceramic solubility influences osteoclast resorption activity, with osteoclasts resorbed BCP most extensively, with an HA/beta-TCP ratio of 25/75, producing typical lobulated, zig-zag track-like resorptive lacunae.

TL;DR: This review focuses on the various chemical and physical treatments that have made the bioprostheses possible, highlighting the chemical agents and the cross-linking mechanism involved.

TL;DR: The marked influence of collagen type and pore characteristics on the phenotypic expression of seeded chondrocytes in porous matrices comprising different collagen types and different pore diameters is demonstrated.

TL;DR: The NiTi alloy showed no cytotoxic, allergic or genotoxic activity, similar to the clinical reference control material AISI 316 LVM stainless steel, and can be regarded as a biologically safe implant material with many promising clinical applications.

TL;DR: In vivo findings of a angiogenesis and migration of neutrophils may be due to persistent release of IL-8 from fibroblasts, supporting the notion that cell proliferation is accelerated indirectly by chitin and its derivatives when these materials are used in vivo.

TL;DR: Alginate capsules with high mannuronic acid content become available for applications such as implantation and have broad application potential as ocular fillings, tissue replacements, microencapsulated growth factors and/or interleukins or slow-release dosage forms of antibodies, surface coatings of sensors and other invasive medical devices.

TL;DR: This review focuses primarily on the delivery of growth factors involved in the processes of wound healing and tissue repair.

TL;DR: Investigation in vivo of the effect of the G-content of the alginate on the biocompatibility of the PLL capsules found the majority of the high-G capsules proved to be overgrown and adherent to the abdominal organs whereas with intermediate-G alginates most capsules were found freely floating in the peritoneal cavity and free of any adhesion of cells.

TL;DR: The results suggest that the microenvironment with a sufficiently high degree of supersaturation of calcium and phosphate ions is crucial for apatite to nucleate and grow in SBF, while the HA crystalline structure is not critical in the nucleation process, as expected.

TL;DR: It seems that surface functional groups and their charge character as well as wettability play important roles for cell adhesion, spreading, and growth.

TL;DR: Electrochemical measurements demonstrated that the transport patterns associated with a spinning disc device approximate the fluid flow and mass transport fields for a disc spinning in an infinite fluid, and this device applies a linear range of forces to attached cells under uniform and constant chemical conditions at the interface.

TL;DR: The synthesis of poly(lactic acid) through polycondensation of the lactic acid monomer gave weight average molecular weights lower than 1.6 x 10(4), whereas ring-opening polymerization of lactides in bulk at 130 degrees C for 72 h using stannous octoate as catalyst produced polylactides with viscosity average molecular weight (Mv).

TL;DR: The adsorption of a range of plasma proteins to metal and polymer surfaces has been examined using surface plasmon resonance (SPR) using a model polystyrene film spun coated directly onto this substrate which confirmed the presence of a closely packed protein layer for all three protein systems.

TL;DR: Findings indicate that the calcium phosphate-rich layer promotes adsorption and concentration of proteins from the TCM, and it is utilized by the osteoblasts to form the mineralized extracellular matrix.

TL;DR: This study used a two-dimensional finite element mesh of a lower first premolar to model two different tooth loading systems which measured either the vertical or the horizontal displacements of this particular tooth.

TL;DR: 1H NMR spectroscopy was utilized to provide direct evidence of the structure of the core-corona structure of these nanoparticles suspended in an aqueous environment and show that the PEG moieties extend out from the nanoparticle core into the aQueous environment, and exhibit chain mobility similar to that of PEG in solution.

TL;DR: It was seen that the covalent immobilization system provides the polymer surfaces with a superior haemocompatibility.

TL;DR: The study indicated that the osteoconductive calcium phosphate coatings have the potential to serve as drug carriers to prevent infection in the setting of total joint arthroplasty.

TL;DR: Several sintering additives for hydroxyapatite (HA) have been tested in order to enhance its sinterability without decomposing the HA and/or decreasing bioactivity and biocompatibility, additionally providing a weak interface for HA ceramics.

TL;DR: The results indicate that the apatite layer deposited on Ti in situ may significantly increase the bone bonding strength by providing a bioactive surface, which allows for an early bone apposition to the implant.

TL;DR: In this work, a precalcification (Pre-Ca) procedure was applied by soaking the two-step treated titanium in Na2HPO4 and then saturated Ca(OH)2 solution before immersion in SCS to accelerate further the CPL precipitation.

TL;DR: Estimations of shear stresses and shear moduli in the bone tissue and at the interface indicated that the increase in bone volume around the implant substantially improved the mechanical capacity.

TL;DR: The cement is a promising material as a bone substitute; however, there is a problem of migration while setting in soft tissue and of exclusion from the bone defects by intense bleeding.

TL;DR: The results show the PEG- hydrogel system to be a good candidate for providing biocompatible interfaces for sensors, especially oxidoreductase-based sensors.

TL;DR: Although desirable from a mechanical point of view, it is shown that coating under residual compression are thermodynamically more stable and, hence, the dissolution of the ionic species, necessary in the exchange between bone and hydroxyapatite coating, can be impeded.

TL;DR: It is suggested that this novel glass-growth factor composite may serve as an effective bone graft material for the repair of osseous defects.