C
C. Ploia
Researcher at Humanitas University
Publications - 3
Citations - 146
C. Ploia is an academic researcher from Humanitas University. The author has contributed to research in topics: Endothelial stem cell & Mesenchymal stem cell. The author has an hindex of 3, co-authored 3 publications receiving 121 citations.
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Journal ArticleDOI
Encapsulated mesenchymal stem cells for in vivo immunomodulation
L. Zanotti,Adelaida Sarukhan,Adelaida Sarukhan,Erica Dander,Marina G. M. Castor,Javier Cibella,Cristiana Soldani,Anna Elisa Trovato,C. Ploia,Giovanni Luca,Mario Calvitti,Francesco Mancuso,Iva Arato,M. Golemac,Nives Jonjić,Andrea Biondi,Riccardo Calafiore,Massimo Locati,Massimo Locati,Giovanna D'Amico,Antonella Viola,Antonella Viola +21 more
TL;DR: Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome and shows overlapping biologic, pathologic, immunophenotypic, and prognostic features.
Journal ArticleDOI
Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1
Lucia Zanotti,Roberta Angioni,Bianca Calì,Cristiana Soldani,C. Ploia,Federica Moalli,Madhu Gargesha,Giovanna D'Amico,Stephen J. Elliman,Gabriella Tedeschi,Elisa Maffioli,Armando Negri,Serena Zacchigna,Adelaida Sarukhan,Jens V. Stein,Antonella Viola +15 more
TL;DR: This study discovers a new and highly efficient general mechanism through which MSC tune down immunity and inflammation, identifies TIMP-1 as a novel biomarker of MSC-based therapy and opens the gate to new therapeutic approaches of inflammatory diseases.
Journal ArticleDOI
Identification of a novel agrin-dependent pathway in cell signaling and adhesion within the erythroid niche.
Achille Anselmo,E Lauranzano,Cristiana Soldani,C. Ploia,Roberta Angioni,Giovanna D'Amico,Adelaida Sarukhan,Cristina Mazzon,Antonella Viola +8 more
TL;DR: It is demonstrated that agrin induces clustering and activation of EphB1 receptors on developing erythroblasts, leading to the activation of α5β1 integrins, which position agrin-EphB 1 as a novel key signaling couple regulating cell adhesion and erythropoiesis.