R
Riccardo Calafiore
Researcher at University of Perugia
Publications - 166
Citations - 4751
Riccardo Calafiore is an academic researcher from University of Perugia. The author has contributed to research in topics: Transplantation & Islet. The author has an hindex of 33, co-authored 158 publications receiving 4222 citations.
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Journal ArticleDOI
Cell encapsulation: promise and progress.
Gorka Orive,Rosa Maria Hernandez,Alicia R. Gascón,Riccardo Calafiore,Thomas Ming Swi Chang,Paul de Vos,Gonzalo Hortelano,David Hunkeler,Igor Lacík,A. M. James Shapiro,José Luis Pedraz +10 more
TL;DR: This commentary discusses the reasons for this, summarizes recent progress in the field and outlines what is needed to bring this technology closer to clinical application.
Journal ArticleDOI
History, challenges and perspectives of cell microencapsulation
Gorka Orive,R.M. Hernández,Alicia R. Gascón,Riccardo Calafiore,Thomas Ming Swi Chang,Paul de Vos,Gonzalo Hortelano,David Hunkeler,Igor Lacík,José Luis Pedraz +9 more
TL;DR: This paper summarizes the current situation in the cell encapsulation field and discusses the main events that have occurred along the way, including capsule manufacture, properties and performance.
Journal ArticleDOI
Microencapsulated Pancreatic Islet Allografts Into Nonimmunosuppressed Patients With Type 1 Diabetes First two cases
Riccardo Calafiore,Giuseppe Basta,Giovanni Luca,Angelo Lemmi,M. Pia Montanucci,G. Calabrese,Leda Racanicchi,Francesca Mancuso,Paolo Brunetti +8 more
TL;DR: A phase 1 pilot clinical trial of microencapsulated TX into 10 nonimmunosuppressed patients with type 1 diabetes, under permission and surveillance by the Italian Ministry of Health is initiated.
Journal ArticleDOI
Long-Term Metabolic and Immunological Follow-Up of Nonimmunosuppressed Patients With Type 1 Diabetes Treated With Microencapsulated Islet Allografts: Four cases
Giuseppe Basta,Pia Montanucci,Giovanni Luca,Carlo Boselli,Giuseppe Noya,Barbara Barbaro,Meirigeng Qi,Katie Kinzer,Jose Oberholzer,Riccardo Calafiore +9 more
TL;DR: The grafts did not elicit any immune response, even in the cases where more than one preparation was transplanted, as a unique finding, compatible with encapsulation-driven “bioinvisibility” of the grafted islets.
Journal ArticleDOI
Mesenchymal Stem Cells Reduce Colitis in Mice via Release of TSG6, Independently of Their Localization to the Intestine.
Emanuela Sala,Marco Genua,Luciana Petti,Achille Anselmo,V. Arena,Javier Cibella,Lucia Zanotti,Silvia D'Alessio,Franco Scaldaferri,Giovanni Luca,Iva Arato,Riccardo Calafiore,Alessandro Sgambato,Sergio Rutella,Massimo Locati,Silvio Danese,Stefania Vetrano +16 more
TL;DR: BM-MSCs injected into mice with colitis do not localize to the intestine but instead form aggregates in the peritoneum where they produce immunoregulatory molecules, including TSG6, that reduce intestinal inflammation.