C
CA Huigens
Researcher at Newcastle University
Publications - 2
Citations - 61
CA Huigens is an academic researcher from Newcastle University. The author has contributed to research in topics: Autoantibody & Receptor. The author has an hindex of 2, co-authored 2 publications receiving 52 citations.
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Journal ArticleDOI
Toll-like receptor-mediated, enhanced production of profibrotic TIMP-1 in monocytes from patients with systemic sclerosis: role of serum factors
Marzena Ciechomska,CA Huigens,Thomas Hügle,Tess A. Stanly,A Gessner,Bridget Griffiths,Timothy R D J Radstake,Sophie Hambleton,Steven O'Reilly,Jacob M van Laar +9 more
TL;DR: This study demonstrates profibrotic properties of circulating monocytes from patients with SSc and a key role for TLR signalling, particularly TLR8, in TIMP-1 secretion and matrix remodelling.
Journal ArticleDOI
Role of B Cells in Rheumatic Autoimmune Disease
TL;DR: An overview of the principal understandings of B cell immunology in autoimmunity and selected rheumatic autoimmune diseases is provided.