C
Caitlyn E. Dickinson
Researcher at Cornell University
Publications - 3
Citations - 144
Caitlyn E. Dickinson is an academic researcher from Cornell University. The author has contributed to research in topics: Recombinant DNA & Gene. The author has an hindex of 2, co-authored 2 publications receiving 128 citations.
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Journal ArticleDOI
Activity-Based Metabolomic Profiling of Enzymatic Function: Identification of Rv1248c as a Mycobacterial 2-Hydroxy-3-oxoadipate Synthase
Luiz Pedro S. de Carvalho,Hong Zhao,Caitlyn E. Dickinson,Nancy Arango,Christopher D. Lima,Steven M. Fischer,Ouathek Ouerfelli,Carl Nathan,Kyu Y. Rhee +8 more
TL;DR: Recombinant Rv1248c catalyzed consumption of alpha-ketoglutarate in a mycobacterial small molecule extract with matched production of 5-hydroxylevulinate (HLA) in a reaction predicted to require glyoxylate, and encodes an HOA synthase.
Journal ArticleDOI
Identification of a chemical that inhibits the mycobacterial UvrABC complex in nucleotide excision repair
Nayef Mazloum,Melanie A. Stegman,Deborah L. Croteau,Bennett Van Houten,Nyoun Soo Kwon,Yan Ling,Caitlyn E. Dickinson,Aditya Venugopal,Mohammad Atif Towheed,Carl Nathan +9 more
TL;DR: Re recombinant UvrA, UvrB, and UvrC from Mtb collectively bound and cleaved plasmid DNA exposed to ultraviolet (UV) irradiation or peroxynitrite and ATBC appears to be a cell-penetrant, selective inhibitor of mycobacterial NER.