Calvin S.H. Ng

TL;DR: The potential benefits of maintaining ventilation and pulmonary artery perfusion during CPB warrant further investigation and the associated physiologic, biochemical, and histologic changes are reviewed.

TL;DR: The high incidence of METΔ14 mutation in sarcomatoid carcinoma suggested that MET inhibition might benefit this specific subgroup of patients and were independent prognostic factors that predicted poorer survival by multivariable analysis.

TL;DR: FOXP3 can act as a co-activator to facilitate the Wnt-b-catenin signaling pathway, inducing EMT and tumor growth and metastasis in NSCLC and co-immunoprecipitation results indicated that FOXP3 could physically interacted with β-catanin and TCF4 to enhance the functions of β-Catenin andTCF4, inducing transcription of Wnt target genes to promote cell proliferation, invasion and EMT induction.

TL;DR: A greater number of ELNs is associated with more-accurate node staging and better long-term survival of resected NSCLC and is recommended as the cut point for evaluating the quality of LN examination or prognostic stratification postoperatively for patients with declared node-negative disease.

TL;DR: Wang et al. as discussed by the authors evaluated the intermediate to long-term QOL in patients with lung cancer following resection, comparing video assisted thoracic surgery (VATS) with thoracotomy.