Canwei Wang

TL;DR: The findings indicate that QKI-5 may exhibit novel anticancer mechanisms by regulating miRNA in NSCLC, and targeting the QKI5∼miR-196b-5p∼GATA6/TSPAN12 pathway may enable effectively treating some NSCLCs.

TL;DR: Treatment of breast cancer cells with WZ35 exerts stronger anti-tumor activities than curcumin both in vitro and in vivo, and novel anti-cancer mechanisms of WZ34 and ROS-YAP-JNK pathway might be a potential therapeutic target for the treatment of breastcancer patients.

TL;DR: It is found that ATL suppresses TNBC cell viability by reactive oxygen species (ROS) accumulation and subsequent ROS‐dependent endoplasmic reticulum (ER) stress both in vitro and in vivo.

TL;DR: Gracillin shows potent efficacy against CRC by inhibiting the STAT3 pathway and should be further explored as a unique STAT3 inhibitor for the treatment of CRC.

TL;DR: In this article , an improved therapeutic strategy for colorectal cancer patients by combining DHA and oxaliplatin treatments was demonstrated. But, the direct target of DHA was not clarified and underlying molecular mechanisms in oxalplatin-mediated anti-tumor activities against CRC are unclear.