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Xiangjie Huang
Researcher at Wenzhou Medical College
Publications - 6
Citations - 233
Xiangjie Huang is an academic researcher from Wenzhou Medical College. The author has contributed to research in topics: Cancer & microRNA. The author has an hindex of 5, co-authored 6 publications receiving 94 citations.
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Journal ArticleDOI
miR-196b-5p–mediated downregulation of TSPAN12 and GATA6 promotes tumor progression in non-small cell lung cancer
Guang Liang,Wei Meng,Xiangjie Huang,Wangyu Zhu,Changtian Yin,Canwei Wang,Matteo Fassan,Yun Yu,Masahisa Kudo,Sisi Xiao,Chengguang Zhao,Peng Zou,Yumin Wang,Xiaokun Li,Carlo M. Croce,Ri Cui +15 more
TL;DR: The findings indicate that QKI-5 may exhibit novel anticancer mechanisms by regulating miRNA in NSCLC, and targeting the QKI5∼miR-196b-5p∼GATA6/TSPAN12 pathway may enable effectively treating some NSCLCs.
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Curcumin derivative WZ35 inhibits tumor cell growth via ROS-YAP-JNK signaling pathway in breast cancer
Lihua Wang,Canwei Wang,Tao Zheying,Liqian Zhao,Zheng Zhu,Wencan Wu,He Ye,Chen Hong,Zheng Bin,Xiangjie Huang,Yun Yu,Linjun Yang,Guang Liang,Ri Cui,Tongke Chen +14 more
TL;DR: Treatment of breast cancer cells with WZ35 exerts stronger anti-tumor activities than curcumin both in vitro and in vivo, and novel anti-cancer mechanisms of WZ34 and ROS-YAP-JNK pathway might be a potential therapeutic target for the treatment of breastcancer patients.
Journal ArticleDOI
Frontiers of MicroRNA Signature in Non-small Cell Lung Cancer.
Xinping Zhu,Masahisa Kudo,Xiangjie Huang,Hehuan Sui,Haishan Tian,Carlo M. Croce,Ri Cui,Ri Cui +7 more
TL;DR: In this article, the authors provide an updated overview of aberrant miRNA signature in non-small cell lung cancer and discuss the possibility of miRNAs becoming a diagnostic and therapeutic tool.
Journal ArticleDOI
Dissecting miRNA signature in colorectal cancer progression and metastasis.
Xiangjie Huang,Xinping Zhu,Yun Yu,Wangyu Zhu,Libo Jin,Xiaodong Zhang,Shaotang Li,Peng Zou,Congying Xie,Ri Cui,Ri Cui +10 more
TL;DR: In this article, the authors provide an updated overview of tumor suppressive and oncogenic miRNAs, circulatory miRNA, and possible causes of dysregulated miRNA in colorectal cancer.
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Alantolactone promotes ER stress-mediated apoptosis by inhibition of TrxR1 in triple-negative breast cancer cell lines and in a mouse model.
Changtian Yin,Changtian Yin,Xuanxuan Dai,Xiangjie Huang,Wangyu Zhu,Xi Chen,Qiulin Zhou,Canwei Wang,Chengguang Zhao,Peng Zou,Guang Liang,Vinothkumar Rajamanickam,Ou-chen Wang,Xiaohua Zhang,Ri Cui +14 more
TL;DR: It is found that ATL suppresses TNBC cell viability by reactive oxygen species (ROS) accumulation and subsequent ROS‐dependent endoplasmic reticulum (ER) stress both in vitro and in vivo.