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Wangyu Zhu
Researcher at Wenzhou Medical College
Publications - 4
Citations - 147
Wangyu Zhu is an academic researcher from Wenzhou Medical College. The author has contributed to research in topics: microRNA & Metastasis. The author has an hindex of 4, co-authored 4 publications receiving 60 citations.
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Journal ArticleDOI
miR-196b-5p–mediated downregulation of TSPAN12 and GATA6 promotes tumor progression in non-small cell lung cancer
Guang Liang,Wei Meng,Xiangjie Huang,Wangyu Zhu,Changtian Yin,Canwei Wang,Matteo Fassan,Yun Yu,Masahisa Kudo,Sisi Xiao,Chengguang Zhao,Peng Zou,Yumin Wang,Xiaokun Li,Carlo M. Croce,Ri Cui +15 more
TL;DR: The findings indicate that QKI-5 may exhibit novel anticancer mechanisms by regulating miRNA in NSCLC, and targeting the QKI5∼miR-196b-5p∼GATA6/TSPAN12 pathway may enable effectively treating some NSCLCs.
Journal ArticleDOI
Dissecting miRNA signature in colorectal cancer progression and metastasis.
Xiangjie Huang,Xinping Zhu,Yun Yu,Wangyu Zhu,Libo Jin,Xiaodong Zhang,Shaotang Li,Peng Zou,Congying Xie,Ri Cui,Ri Cui +10 more
TL;DR: In this article, the authors provide an updated overview of tumor suppressive and oncogenic miRNAs, circulatory miRNA, and possible causes of dysregulated miRNA in colorectal cancer.
Journal ArticleDOI
Alantolactone promotes ER stress-mediated apoptosis by inhibition of TrxR1 in triple-negative breast cancer cell lines and in a mouse model.
Changtian Yin,Changtian Yin,Xuanxuan Dai,Xiangjie Huang,Wangyu Zhu,Xi Chen,Qiulin Zhou,Canwei Wang,Chengguang Zhao,Peng Zou,Guang Liang,Vinothkumar Rajamanickam,Ou-chen Wang,Xiaohua Zhang,Ri Cui +14 more
TL;DR: It is found that ATL suppresses TNBC cell viability by reactive oxygen species (ROS) accumulation and subsequent ROS‐dependent endoplasmic reticulum (ER) stress both in vitro and in vivo.
Journal ArticleDOI
miR-196b-5p -mediated downregulation of FAS promotes NSCLC progression by activating IL6-STAT3 signaling
Xiangjie Huang,Sisi Xiao,Xinping Zhu,Yun Yu,Meng Cao,Xiaodong Zhang,Shaotang Li,Wangyu Zhu,Fengjiao Wu,Xiaohui Zheng,Libo Jin,Libo Jin,Congying Xie,Xiaoying Huang,Peng Zou,Peng Zou,Xiaokun Li,Xiaokun Li,Ri Cui,Ri Cui +19 more
TL;DR: It is found that miR-196b-5p promotes lung cancer cell proliferation and colony formation by directly targeting tumor suppressor, FAS, and suggested that targeting the miR/FAS/NFkB/IL6/STAT3 pathway might be a promising therapeutic strategy in treating NSCLC.