Carla I. Tasca

TL;DR: Investigating the effects of QA on the glutamatergic system from rat brain, it is demonstrated that QA (from 0.1 to 10mM) had no effect on synaptosomal L-[3H]glutamate uptake, and data provide additional evidence that neurotoxicity ofQA may be also related to disturbances on the glutamate transport system, which could result in the neurological manifestations observed when this organic acid accumulates in the brain.

TL;DR: Results indicate that short bouts of exercise represent a viable behavioral strategy to improve cognition and synaptic plasticity in aging rats which should be taken into account in further studies addressing the effects of physical exercise in aging subjects.

TL;DR: It is demonstrated that glyphosate-induced neurotoxicity in immature rats following acute and chronic pesticide exposure might lead to excessive extracellular glutamate levels and consequently to glutamate excitotoxicity and oxidative stress in rat hippocampus.

TL;DR: This paper describes the step-by-step procedure to expose cultures and acute slices to OGD, focusing on the most suitable methods for assessing cellular death and/or viability.

TL;DR: Atorvastatin treatment was neuroprotective against cell degeneration induced by Aβ(1-40), reducing inflammatory and oxidative responses and increasing the expression of glutamatergic transporters, and the present findings suggest that the spatial learning and memory deficits inducedBy Aβ peptides in rodents may not be entirely related to neuronal damage.