C
Carlos Alberto von Mühlen
Researcher at Scripps Research Institute
Publications - 25
Citations - 1583
Carlos Alberto von Mühlen is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Autoantibody & Antigen. The author has an hindex of 10, co-authored 23 publications receiving 1260 citations.
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Journal ArticleDOI
Autoantibodies in the diagnosis of systemicrheumatic diseases
TL;DR: Several of the antigen -autoantibody systems found in systemic lupus erythematosus are discussed, addressing their clinical significance, common detection methods, immunogenetic associations, and the molecular and cellular biology of the cognate antigens.
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Report of the First International Consensus on Standardized Nomenclature of Antinuclear Antibody HEp-2 Cell Patterns 2014–2015
Edward K. L. Chan,Jan Damoiseaux,Orlando Gabriel Carballo,Karsten Conrad,Wilson de Melo Cruvinel,Paulo Luiz Carvalho Francescantonio,Marvin J. Fritzler,Ignacio García-De La Torre,Manfred Herold,Tsuneyo Mimori,Minoru Satoh,Carlos Alberto von Mühlen,Luis Eduardo Coelho Andrade +12 more
TL;DR: The current report summarizes the collective agreements with input from the host Brazilian and international communities that represented research, clinical, and diagnostic service laboratories to establish a consensus on the nomenclature of staining patterns observed in the antinuclear antibody (ANA) indirect immunofluorescence test on HEp-2 cells.
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Clinical relevance of HEp-2 indirect immunofluorescent patterns: the International Consensus on ANA patterns (ICAP) perspective
Jan Damoiseaux,Luis Eduardo Coelho Andrade,Orlando Gabriel Carballo,Karsten Conrad,Paulo Luiz Carvalho Francescantonio,Marvin J. Fritzler,Ignacio García-De La Torre,Manfred Herold,Werner Klotz,Wilson de Melo Cruvinel,Tsuneyo Mimori,Carlos Alberto von Mühlen,Minoru Satoh,Edward K. L. Chan +13 more
TL;DR: The ICAP consensus is presented on the clinical relevance of the 29 distinct HEp-2 IIFA patterns: this clinical relevance is primarily defined within the context of the suspected disease and includes recommendations for follow-up testing.
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Induction of Cytoplasmic Rods and Rings Structures by Inhibition of the CTP and GTP Synthetic Pathway in Mammalian Cells
Wendy C. Carcamo,Minoru Satoh,Hideko Kasahara,Naohiro Terada,Takashi Hamazaki,Jason Y F Chan,Bing Yao,Stephanie Tamayo,Giovanni Covini,Carlos Alberto von Mühlen,Edward K. L. Chan +10 more
TL;DR: The availability of specific markers for these conserved structures and the ability to induce formation in vitro will allow further investigations in structure and function of RR in many biological systems in health and diseases.
Journal ArticleDOI
International consensus on ANA patterns (ICAP): the bumpy road towards a consensus on reporting ANA results
Jan Damoiseaux,Carlos Alberto von Mühlen,Ignacio García-De La Torre,Orlando Gabriel Carballo,Wilson de Melo Cruvinel,Paulo Luiz Carvalho Francescantonio,Marvin J. Fritzler,Manfred Herold,Tsuneyo Mimori,Minoru Satoh,Luis Eduardo Coelho Andrade,Edward K. L. Chan,Karsten Conrad +12 more
TL;DR: The International Consensus on ANA Patterns was initiated as a workshop aiming to thoroughly discuss and achieve consensus regarding the morphological patterns observed in the indirect immunofluorescence assay on HEp-2 cells, but implications for existing diagnostic/classification criteria for ANA-associated diseases in particular hampered a final consensus.