Caroline E. Ford

TL;DR: It is shown that the structural organization of these DDR-related genes is highly conserved throughout evolution suggesting that invertebrate DDRs may also function as receptors for collagen, and could help attract new research on DDRs from a variety of different fields.

TL;DR: It is concluded that whereas altered expression of DDRs may contribute to malignant progression of NSCLC, it is unlikely that this results from mutations in the DDR1 and DDR2 genes that were investigated.

TL;DR: MMTV-like gene sequences are found in only some human populations and are rarely found in normal human breast tissue from all populations, suggesting they are not present in the normal human genome and have been acquired.

TL;DR: The role of the Wnt signalling pathway in acquired resistance to Tamoxifen is supported and combinatorial treatment with endocrine agents and Wnt pathway inhibitors may be a useful therapeutic option in the future for a subset of breast cancer patients.

TL;DR: Results indicate that modulation of a single upstream gatekeeper of Wnt signalling can have effects on downstream WNT signalling and ovarian cancer cell behaviour, as mediated through epithelial to mesenchymal plasticity (EMP) and the possibility that SFRP4 may be used both diagnostically and therapeutically in epithelial ovarian cancer.