Caroline Misslin

TL;DR: Primary prophylaxis with itraconazole among immunocompromised patients seems warranted and disseminated histoplasmosis is the most common febrile opportunistic infection in western French Guiana.

TL;DR: The present study shows that ¾ of the patients with disseminated histoplasmosis were profoundly immunocompromised and had been diagnosed for HIV within the past year, and over time there was a significant gradual decline in early death.

TL;DR: Targeted efforts through a bi-national collaboration are needed to address the specific issues of cross-border patients to reach the 90*3 UNAIDS's diagnosis, link to care and treatment targets and better control the local epidemic.

TL;DR: Within French Guiana, despite a younger age among foreigners than French patients, the risk factors, mechanisms, and outcomes were homogenous across socioeconomic strata, and the observed differences between the two contrasted French territories suggested that, beyond health inequalities, the epidemiology of cardiovascular risk factors may differ betweenFrench Guiana and mainland France.

TL;DR: In this article, the authors describe the frequency and manifestations of disseminated histoplasmosis in French Guiana, and compare patients with disseminated H. capsulatum with or without gastrointestinal involvement.