C
Carsten Kamphues
Researcher at Charité
Publications - 73
Citations - 1247
Carsten Kamphues is an academic researcher from Charité. The author has contributed to research in topics: Medicine & Colorectal cancer. The author has an hindex of 17, co-authored 54 publications receiving 869 citations. Previous affiliations of Carsten Kamphues include German Cancer Research Center & Humboldt University of Berlin.
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Journal ArticleDOI
Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer
Georgios A. Margonis,Stefan Buettner,Stefan Buettner,Nikolaos Andreatos,Yuhree Kim,Doris Wagner,Kazunari Sasaki,Andrea Beer,Christoph Schwarz,Inger Marie Løes,Inger Marie Løes,Maria Anna Smolle,Carsten Kamphues,Jin He,Timothy M. Pawlik,Klaus Kaczirek,George A. Poultsides,Per Eystein Lønning,Per Eystein Lønning,John L. Cameron,Richard A. Burkhart,Armin Gerger,Federico Aucejo,Martin E. Kreis,Christopher L. Wolfgang,Matthew J. Weiss +25 more
TL;DR: The presence of the V600E BRAF mutation was associated with worse prognosis and increased risk of recurrence and the V 600E mutation was not only a stronger prognostic factor than KRAS but also was the strongest prognostic determinant in the overall cohort.
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Postoperative Complications Deteriorate Long-Term Outcome in Pancreatic Cancer Patients
Carsten Kamphues,Roberta Bova,Dorothee Schricke,Michael Hippler-Benscheidt,Frederick Klauschen,Albrecht Stenzinger,Daniel Seehofer,Matthias Glanemann,Peter Neuhaus,Marcus Bahra +9 more
TL;DR: It is demonstrated that severe postoperative complications have a strong impact on the long-term survival of patients with pancreatic head cancer comparable to tumor characteristics, such as lymph node status, grading, or R status.
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Prognostic Factors Change Over Time After Hepatectomy for Colorectal Liver Metastases: A Multi-institutional, International Analysis of 1099 Patients.
Georgios A. Margonis,Stefan Buettner,Nikolaos Andreatos,Doris Wagner,Kazunari Sasaki,Carlotta Barbon,Andrea Beer,Carsten Kamphues,Inger Marie Løes,Jin He,Timothy M. Pawlik,Klaus Kaczirek,George A. Poultsides,Per Eystein Lønning,Per Eystein Lønning,John L. Cameron,Hans Joerg Mischinger,Federico Aucejo,Martin E. Kreis,Christopher L. Wolfgang,Matthew J. Weiss +20 more
TL;DR: The impact of genetic, surgery-related, and clinicopathologic factors on OS and CS3 changed dramatically over time, with BRAF mutation status dominated prognosis in the first year, whereas positive surgical margins and resected extrahepatic disease determined prognosis thereafter.
Journal ArticleDOI
Laparoscopic versus open gastrectomy for locally advanced gastric cancer: a systematic review and meta-analysis of randomized controlled studies
Katharina Beyer,Ann-Kathrin Baukloh,Carsten Kamphues,Hendrik Seeliger,Claus-Dieter Heidecke,Martin E. Kreis,M. Patrzyk +6 more
TL;DR: Laparoscopic gastrectomy with D2 lymphadenectomy can be performed with equivalent overall short-term morbidity and mortality versus the open approach for locally advanced gastric cancer, indicating oncological equivalence of both approaches.
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Who is at risk for diagnostic discrepancies? Comparison of pre- and postmortal diagnoses in 1800 patients of 3 medical decades in East and West Berlin.
Daniel Wittschieber,Frederick Klauschen,Anna-Christin Kimmritz,Moritz von Winterfeld,Carsten Kamphues,Hans-Joachim Scholman,Andreas Erbersdobler,Heidi Pfeiffer,Carsten Denkert,Manfred Dietel,Wilko Weichert,Jan Budczies,Albrecht Stenzinger,Albrecht Stenzinger +13 more
TL;DR: A well-powered analysis revealed a significant rate of class-I-discrepancies indicating that autopsies are still of value, and identified risk profiles may aid both pathologists and clinicians to identify patients at increased risk for a discrepant diagnosis and possibly suboptimal treatment intra vitam.