C
Catherine Zwahlen
Researcher at University of Lausanne
Publications - 38
Citations - 2264
Catherine Zwahlen is an academic researcher from University of Lausanne. The author has contributed to research in topics: Magnetization & Nuclear Overhauser effect. The author has an hindex of 17, co-authored 38 publications receiving 2198 citations. Previous affiliations of Catherine Zwahlen include Swiss Institute of Bioinformatics & Florida State University.
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Journal ArticleDOI
Methods for Measurement of Intermolecular NOEs by Multinuclear NMR Spectroscopy: Application to a Bacteriophage λ N-Peptide/boxB RNA Complex
Catherine Zwahlen,Pascale Legault,Sebastien J. F. Vincent,Jack Greenblatt,and Robert Konrat,Lewis E. Kay +5 more
TL;DR: Improved spectra are obtained relative to data recorded with other purging schemes and structural information obtained for a complex of the amino-terminal arginine rich domain of the N protein from bacteriophage λ and boxB RNA using the new methodology is presented.
Journal ArticleDOI
The BBXB Motif of RANTES Is the Principal Site for Heparin Binding and Controls Receptor Selectivity
Amanda E. I. Proudfoot,Sarah J. Fritchley,Frédéric Borlat,Jeffrey P. Shaw,Francis Vilbois,Catherine Zwahlen,Alexandra Trkola,David Marchant,Paul R. Clapham,Timothy N. C. Wells +9 more
TL;DR: Mutation of the 44RKNR47 site reduced the selectivity of RANTES binding to different GAGs, and the triple 40s mutant was able to inhibit HIV-1 infectivity, but consistent with its abrogated GAG binding capacity, it no longer induced enhanced infectivity at high concentrations.
Journal ArticleDOI
A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization
Anne Christine Butty,Nathalie Perrinjaquet,Audrey Petit,Malika Jaquenoud,Jeffrey E. Segall,Kay Hofmann,Catherine Zwahlen,Matthias Peter +7 more
TL;DR: The results suggest that Bem1 functions in a positive feedback loop: local activation of Cdc24 produces Cdc42–GTP, which recruits BEM1, which stabilizes CDC24 at the site of polarization, leading to apical growth.
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neXtProt: a knowledge platform for human proteins
Lydie Lane,Ghislaine Argoud-Puy,Aurore Britan,Isabelle Cusin,Paula D. Duek,Olivier Evalet,Alain Gateau,Pascale Gaudet,Anne Gleizes,Alexandre Masselot,Catherine Zwahlen,Amos Marc Bairoch +11 more
TL;DR: An overview of the database and the data integration process is presented and the key future directions of neXtProt are laid out that consider the necessary steps to make neXTProt the one-stop-shop for all research projects focusing on human proteins.
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neXtProt: organizing protein knowledge in the context of human proteome projects.
Pascale Gaudet,Ghislaine Argoud-Puy,Isabelle Cusin,Paula D. Duek,Olivier Evalet,Alain Gateau,Anne Gleizes,Mario Pereira,Monique Zahn-Zabal,Catherine Zwahlen,Amos Marc Bairoch,Lydie Lane +11 more
TL;DR: How neXtProt contributes to prioritize C-HPP efforts and integrates C-hPP results with other research efforts to create a complete human proteome catalog is described.