Showing papers by "Cecília M. P. Rodrigues published in 1995"

TL;DR: Sulfation of ursodeoxycholate, specifically at the C-7 position, protects the molecule from bacterial degradation and inhibits its intestinal absorption, thereby facilitating delivery to the colon.

TL;DR: Compared with ursodeoxycholic acid, tauroursodeoxy cholic acid induces a greater decrease in the percent composition of more hydrophobic bile acids within the pool, limits lithocholate formation, and increases hepatic ursODEoxycholate concentration.