Showing papers in "Gastroenterology in 1995"

TL;DR: Small changes in diet can alter the balance of colonic bacteria towards a potentially healthier microflora, and a 15-g.day-1 dietary addition of oligofructose or inulin led to Bifidobacterium becoming the numerically predominant genus in feces.

TL;DR: The hypothesis that TNF is of major importance in the pathogenesis of Crohn's disease is supported, and treatment with cA2 was safe and may be useful in patients with Crohn’s disease that is unresponsive to steroid treatment.

TL;DR: Because altered rectal perception is present in almost all patients with IBS and perception thresholds correlate with temporal changes in retrospective symptom severity, altered Rectal perception represents a reliable biological marker of IBS.

TL;DR: Chronic gastrointestinal symptoms and histological changes of the esophagus unresponsive to standard treatments for gastroesophageal reflux were improved by the use of elemental formulas.

TL;DR: There is a need for integrated research into the basic mechanisms of regulatory control of the intestinal barrier function and the potential and possible shortcomings of noninvasive tests of intestinal permeability.

TL;DR: This work presents a novel, scalable, scalable and scalable approach that can be applied to the rapidly changing and rapidly changing landscape of gastroenterological care.

TL;DR: Metronidazole therapy for 3 months decreases the severity of early recurrence of Crohn's disease in the neoterminal ileum after resection and seems to delay symptomatic recurrence.

TL;DR: The separation of functional gastrointestinal symptoms into dyspepsia, its subgroups, and IBS may be inappropriate.

TL;DR: Intestinal sterilization prevented alcohol-induced liver injury in the rat, supporting the idea that hypermetabolism and consequent hypoxia caused by activation of Kupffer's cells by endotoxin is involved in the mechanism.

TL;DR: The noninvasive UBT and IgG serology test are as accurate in predicting H. pylori status in untreated patients as the invasive tests of CLO and Warthin-Starry.

TL;DR: In this article, the effect of Helicobacter pylori infection on acid secretion was examined basally and in response to gastrin-releasing peptide (GRP) and gastrin in healthy volunteers.

TL;DR: The 3-year interval screening more than halves the CRC rate in at-risk members of families with HNPCC and seems to prevent CRC deaths.

TL;DR: The economic impact of IBS is significant and a better understanding of the determinants of these costs is needed so that cost-saving strategies can be implemented.

TL;DR: Predicted quality survival at home for several months, rather than a specific diagnosis, seems to be the soundest justification for HPEN and its role in terminal conditions and patients without primary gastrointestinal diseases needs further evaluations.

TL;DR: Survival was primarily determined by the presence of liver metastases, and the frequency of Liver metastases depends on the size and location of the primary tumor and on the Presence of MEN-1 at the initial presentation.

TL;DR: A large body of work pertaining to studies of eicosanoids in the gastrointestinal tract is distill to present a clear summary of this area of gastroenterology so that future research can be directed in a logical and productive manner.

TL;DR: The cloned human liver organic anion transporter is closely related to, but probably not identical to, the previously cloned rat liver transporter and its additional localization in a variety of extrahepatic tissues suggests that it plays a fundamental role in overall transepithelial organic anions transport of the human body.

TL;DR: Adenocarcinomas of the esophagogastric junction are associated with short and long segments of Barrett's esophagus, and larger cancers probably overgrow and conceal the underlying specialized columnar epithelium from which they arise.

TL;DR: Comparing by meta-analysis the likelihood of clinical response to liquid diet therapy vs. corticosteroids and the importance of formula composition to efficacy, data analyzed do not support an advantage to elemental feedings compared with a polymeric formulation.

TL;DR: IL-10 down-regulates the enhanced secretion as well as messenger RNA levels of proinflammatory cytokines by IBD mononuclear phagocytes in vitro and in vivo and can restore diminished in vitro IL-1 receptor antagonist/IL-1 beta ratios in IBD to normal levels.

TL;DR: A provisional model for hepatocyte necrosis is developed that may be applicable to cell necrosis in general and the advances in the understanding of the cellular mechanisms of necrotic injury are highlighted.

TL;DR: Protection was enhanced by the copresence of human colonic mucin glycoproteins when added with human spasmolysin or human intestinal trefoil factor, which helps protect gastrointestinal mucosa from a variety of insults.

TL;DR: Contrast echocardiography is the most useful screening test for intrapulmonary vasodilatation and may be positive more frequently than lung perfusion scans in patients with HPS.

TL;DR: The biology and significance of the epidermal growth factor (EGF) family is reviewed, with particular emphasis on understanding the integrated function of the family and the relationships between family members in the context of gastrointestinal physiology and pathophysiology.

TL;DR: The colocalization of tyrosine nitration with iNOS immunoreactivity suggests that inducible NO synthase may be responsible for tissue injury and the formation of NO-dependent nitrating species, potentially peroxynitrite.

TL;DR: FOBT alone is the most cost-effective of the programs, but the cost is sensitive to several key variables, including compliance, which is an important determinant of effectiveness of all of the screening programs.

TL;DR: In ambulant healthy subjects, accurate continuous recording of lower esophageal sphincter (LES) function is possible, reflux usually occurs during transient LES relaxations, and straining is not a major factor in the induction of reflux.

TL;DR: Severe acetaminophen-induced hepatotoxicity remains a serious condition, but the increasing use of N-acetylcysteine, advances in medical management, and the increasing availability of transplantation have resulted in a significant improvement in survival rates.