K
Kenneth D.R. Setchell
Researcher at Cincinnati Children's Hospital Medical Center
Publications - 312
Citations - 29263
Kenneth D.R. Setchell is an academic researcher from Cincinnati Children's Hospital Medical Center. The author has contributed to research in topics: Bile acid & Cholic acid. The author has an hindex of 80, co-authored 291 publications receiving 27363 citations. Previous affiliations of Kenneth D.R. Setchell include Boston Children's Hospital & University of Perugia.
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Soy intake and cancer risk: A review of the in vitro and in vivo data
TL;DR: There is sufficient evidence of a protective effect to warrant continued investigation of the role of soyfoods in cancer prevention, and in vitro, animal, and epidemiological data are examined.
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The Clinical Importance of the Metabolite Equol—A Clue to the Effectiveness of Soy and Its Isoflavones
TL;DR: It is now apparent that there are two distinct subpopulations of people and that "bacterio-typing" individuals for their ability to make equol may hold the clue to the effectiveness of soy protein diets in the treatment or prevention of hormone-dependent conditions.
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Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones.
TL;DR: The importance of a plant-based diet is evident from the current dietary recommendations that emphasize an increase in the proportion and amount of fruit and vegetables that should be consumed, and interpretation of the role of individual components of the diet is difficult from epidemiologic and dietary studies.
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Dietary Isoflavones: Biological Effects and Relevance to Human Health
TL;DR: This review focuses on the more recent studies pertinent to this field and includes, where appropriate, the landmark and historical literature that has led to the exponential increase in interest in phytoestrogens from a clinical nutrition perspective.
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Bioavailability of Pure Isoflavones in Healthy Humans and Analysis of Commercial Soy Isoflavone Supplements
Kenneth D.R. Setchell,Nadine M Brown,Pankaj B. Desai,Linda Zimmer-Nechemias,Brian Wolfe,Wayne T Brashear,Abby S. Kirschner,Aedin Cassidy,James E. Heubi +8 more
TL;DR: Differences in the pharmacokinetics of isoflavone glycosides compared with their respective beta-glycosides are demonstrated and indicate a need for improvement in quality assurance and standardization of such products.