Cezary Szczylik

TL;DR: In this subpopulation of patients with metastatic renal cell carcinoma, antiangiogenic therapy, such as sorafenib, could be an effective preventive therapy for brain metastases in advanced RCC.

TL;DR: Although progress has been made applying 3D technology to CSC research, this technology could be further utilized and a greater number of 3D kits dedicated specifically to C SCs should be implemented.

TL;DR: The modulation by rhEPO of tumor cell response to anticancer agents is coincident with modulation of multiple signaling pathways, BCL-2 family proteins, caspases and NFkB.

TL;DR: This review concentrates on the interactions between stromal and healthy cells from the TME in cancer development and describes mutations, genes and proteins expression pattern that are involved in tumour development in target organ.

TL;DR: For an actively treated patient with cancer, cancer remains the main life-threatening disease during the COVID-19 pandemic and the need for more attentive psychological care should be provided especially to female patients, patients with breast cancer, those under 65 years of age and treated with curative intention, as these factors are associated with a higher level of anxiety.