Chance Bloomer

TL;DR: A high prognostic score (composite 4 gene signature—DPP7/2, YWHAB, MCM4 and FBXO46) was found to be a significant predictor of poor prognosis in CRC patients and identified a novel 4 gene prognostic signature that has clinical utility in colorectal cancer.

TL;DR: A structured analysis of the available literature from several databases is performed to guide future research and clinical trials on the microbiome with the hopes of improving screening techniques, decreasing treatment toxicities, and improving survival for patients with HNSCC.

TL;DR: A 67-year-old female with stage IV cutaneous melanoma who received first-line pembrolizumab was an effective means of treating the patient while sparing them from prolonged corticosteroids, the first case of its use to treat an aortitis irAE to the authors' knowledge.

TL;DR: The case of a 72-year-old patient with a heavily pre-treated, advanced maxillary sinus squamous cell cancer with distant metastases who developed complete response (CR) with only three administrations of a programmed death 1 inhibitor after treatment interference by a severe herpes zoster infection, based on the related alpha-herpesvirus varicella zoster virus (VZV).

TL;DR: In this article , the authors created a registry of all patients who received at least one dose of an ICI for any indication between 2/1/2011 and 4/7/2022 at a comprehensive cancer center and its outreach clinics.