C
Changjun Yu
Researcher at California Institute of Technology
Publications - 5
Citations - 853
Changjun Yu is an academic researcher from California Institute of Technology. The author has contributed to research in topics: Oligonucleotide & Ferrocene. The author has an hindex of 5, co-authored 5 publications receiving 835 citations.
Papers
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Journal ArticleDOI
Electron Transfer at Electrodes through Conjugated “Molecular Wire” Bridges
Stephen E. Creager,Changjun Yu,Cindy Bamdad,Steve O'Connor,Tanya MacLean,Eric Lam,Yoochul Chong,Gary T. Olsen,Jiye Luo,Michael Gozin,Jon F. Kayyem +10 more
TL;DR: In this paper, the electron transfer rates and electronic coupling factors for ferrocene groups attached to gold electrodes via oligo(phenylethynyl) "molecular wire" bridges of variable length and structure are reported.
Journal ArticleDOI
Electronic Detection of Single-Base Mismatches in DNA with Ferrocene-Modified Probes
Changjun Yu,Yanjian Wan,Handy Yowanto,Jie Li,Chunlin Tao,Matthew D. James,Christine L. Tan,Gary Blackburn,Thomas J. Meade +8 more
TL;DR: A new ferrocene-containing phosphoramidite 9 that provides a range of detectable redox potentials is described and thermal stability analysis of these metal-containing DNA oligonucleotides indicates that incorporation of 9 resulted in no destabilization of the duplex.
Journal ArticleDOI
Soluble Ferrocene Conjugates for Incorporation into Self-Assembled Monolayers.
TL;DR: The generation of an arenethiol anion during base- or fluoride-catalyzed deprotection has been characterized and several new reactions for preparing werenethiol-protected compounds are described.
Journal ArticleDOI
Uridine-Conjugated Ferrocene DNA Oligonucleotides: Unexpected Cyclization Reaction of the Uridine Base
Changjun Yu,Handy Yowanto,Yanjian Wan,Thomas J. Meade,Yoochul Chong,Michael J. Strong,Leslee H. Donilon,Jon F. Kayyem,Michael Gozin,Gary Blackburn +9 more
TL;DR: Ferrocene (Fc) and its derivatives are attractive electrochemical probes because of their stability and convenient synthetic chemistry as mentioned in this paper, and Ferrocene-containing DNA oligonucleotides have been prepared by attaching ferrocenyl moieties to the 5' termini.
Patent
Sequence determination of nucleic acids using electronic detection
Robert M. Umek,Gary Blackburn,Bruce D. Irvine,Robert H. Terbrueggen,Changjun Yu,Jost Vielmetter +5 more
TL;DR: In this article, the use of self-assembled monolayers to detect nucleic acids, particularly alterations such as nucleotide substitutions (mismatches) and single nucleotide polymorphisms (SNPs).