C
Chao Han
Publications - 3
Citations - 32
Chao Han is an academic researcher. The author has contributed to research in topics: Wnt signaling pathway & Adipogenesis. The author has an hindex of 1, co-authored 3 publications receiving 5 citations.
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Journal ArticleDOI
Fibronectin 1 activates WNT/β-catenin signaling to induce osteogenic differentiation via integrin β1 interaction.
Chengliang Yang,Chong Wang,Jing Zhou,Qingyang Liang,Feng He,Feng Li,Ye Li,Jinzhong Chen,Fan Zhang,Chao Han,Jia Liu,Kai Li,Yujin Tang +12 more
TL;DR: Fibronectin 1 (FN-1) promoted differentiation and mineralization of osteoblasts by activating the WNT/β-catenin pathway, in cultured pre-osteoblasts, and was revealed as a potential therapeutic strategy for improvement of bone formation in osteoporosis.
Journal ArticleDOI
Carfilzomib alleviated osteoporosis by targeting PSME1/2 to activate Wnt/β-catenin signaling.
Guido T. Bommer,Fan Zhang,Shokouh Attarilar,Guido T. Bommer,Stanley Devine,Kegong Xie,Chao Han,Yesenia Uribe,Qingyang Liang,Ke Huang,Changgong Lan,Chong Wang,Chengliang Yang,Liqiang Wang,Masoud Mozafari,Kai Li,Jia Liu,Yujin Tang +17 more
TL;DR: Wang et al. as discussed by the authors found that protein levels of proteasome activator subunit 1/2 (PSME1/2) increased in osteoporosis and accumulated mostly in osteoblasts and osteoclasts.
Journal ArticleDOI
HA15 alleviates bone loss in ovariectomy-induced osteoporosis by targeting HSPA5.
Chao Han,Kegong Xie,Chengliang Yang,Fan Zhang,Qingyang Liang,Changgong Lan,Jian Chen,Ke Huang,Jia Liu,Kai Li,Yujin Tang,Liqiang Wang +11 more
TL;DR: In this paper, heat shock protein family A (Hsp70) member 5 (HSPA5) was shown to significantly accumulate in osteoblasts and adipocytes, but not in osteoclasts in bone sections from aged and postmenopausal OP mice.