C
Charles E. Wade
Researcher at University of Texas Health Science Center at Houston
Publications - 609
Citations - 40501
Charles E. Wade is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Resuscitation & Injury Severity Score. The author has an hindex of 90, co-authored 579 publications receiving 36280 citations. Previous affiliations of Charles E. Wade include University of California, Davis & University of Texas Health Science Center at San Antonio.
Papers
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Journal ArticleDOI
Development and resuscitation of a sedated, mature male miniature swine severe hemorrhage model.
John W. Burns,Lisa A. Baer,Erica J Hagerman,Bryan S. Jordan,Johnny J Nelson,Andriy I. Batchinsky,Leopoldo C. Cancio,John A. Jones,Michael A. Dubick,Charles E. Wade +9 more
TL;DR: A sedated, sexually mature male miniature swine severe hemorrhage model has been successfully developed, resuscitated with Hextend and used to evaluate E2 as a small volume resuscitation product.
Mechanistic determinates of the acute coagulopathy of trauma (ACoT) in patients requiring emergency surgery
TL;DR: It is revealed that ACoT is independently associated with both shock (base deficit) and tissue injury, and tissue Injury is a significant contributor to the development of early ACoG regardless of blunt or penetrating mechanism.
Journal ArticleDOI
Hypocoagulability in Traumatic Brain Injury as Measured by Traditional Means and Thrombelastography
Sherry L Sixta,Jessica C. Cardenas,Ryan S. Kitagawa,Charles E. Wade,John B. Holcomb,Bryan A. Cotton +5 more
TL;DR: No difference in coagulopathy prevalence was observed between TBI and non-TBI patients by CCT, but a higher prevalence of coagULopathy by r-TEG values was found in isolated TBI patients and was predictive of mortality.
Journal ArticleDOI
Association of Changes in Antithrombin Activity Over Time With Responsiveness to Enoxaparin Prophylaxis and Risk of Trauma-Related Venous Thromboembolism.
Laura Vincent,Michael M Talanker,Dakota D Butler,Xu Zhang,Jeanette M. Podbielski,Yao Wei W Wang,Amber Chen-Goodspeed,Selina L Hernandez Gonzalez,Erin E. Fox,Bryan A. Cotton,Charles E. Wade,Jessica C. Cardenas +11 more
TL;DR: A single-center, prospective cohort study at a level 1 trauma center to examine time-dependent changes in antithrombin activity, responsiveness to enoxaparin, as measured by anti-factor Xa (anti-FXa) levels, and incidence of VTE after severe trauma and to assess the association of ex vivo antithROMbin supplementation with patients' sensitivity to en oxaparin prophylaxis.
Journal Article
Alterations in the volume stimulus-renal response relationship during exposure to simulated microgravity.
Victor A. Convertino,S. C. Koenig,J. W. Fanton,C. A. Reister,F. A. Gaffney,D. A. Ludwig,D. L. Ewert,Charles E. Wade +7 more
TL;DR: It appeared that the lower CVP may reflect a new operating point about which vascular volume is regulated, and attenuated ANP and PRA responses during vascular volume loading may contribute to depressed UVR in low gravity exposure.