C
Charles E. Wade
Researcher at University of Texas Health Science Center at Houston
Publications - 609
Citations - 40501
Charles E. Wade is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Resuscitation & Injury Severity Score. The author has an hindex of 90, co-authored 579 publications receiving 36280 citations. Previous affiliations of Charles E. Wade include University of California, Davis & University of Texas Health Science Center at San Antonio.
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Journal ArticleDOI
Validation of sepsis screening tool using StO2 in emergency department patients.
TL;DR: Heart rate, respiratory rate, and temperature have good diagnostic potential for the early identification of sepsis among emergency department triage personnel and early evidence suggests StO2 may play a complementary and synergistic role in theEarly identification of Sepsis by triage Personnel.
Journal Article
Dextran concentrations in plasma and urine following administration of 6% dextran-70/7.5% NaCl to hemorrhaged and euvolemic conscious swine.
TL;DR: Data show that HSD ameliorates the effects of hemorrhage on cardiovascular and renal function and suggest that plasma clearance of dextran may be affected by hemorrhage.
Journal ArticleDOI
Effects of the antiglucocorticoid RU 486 on adrenal function in dogs.
Charles E. Wade,Irving M. Spitz,Pekka Lähteenmäki,Oskari Heikinheimo,Dorothy T. Krieger,C. Wayne Bardin +5 more
TL;DR: It is concluded that in dogs a daily RU 486 dose of 5 mg/kg does not alter adrenal function, whereas higher doses induce increases in plasma ACTH and cortisol concentrations, which suggests that there was no functional deficiency of cortisol at the renal tubule or it was overshadowed by augmented mineralocorticoid production and action.
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Alternative end points for trauma studies: A survey of academic trauma surgeons.
Zeinab M. Alawadi,Zeinab M. Alawadi,Eric LeFebvre,Erin E. Fox,Deborah J. del Junco,Bryan A. Cotton,Bryan A. Cotton,Charles E. Wade,Charles E. Wade,John B. Holcomb,John B. Holcomb +10 more
TL;DR: There is strong interest in finding efficient end points in trauma research that are both specific and reflect the changing epidemiology of trauma death.
Journal ArticleDOI
Do-not-resuscitate orders in trauma patients may bias mortality-based effect estimates: An evaluation using the PROMMTT study
Charles E. Wade,Deborah J. del Junco,Erin E. Fox,Bryan A. Cotton,Mitchell J. Cohen,Peter Muskat,Martin A. Schreiber,Mohammad H. Rahbar,R. Michelle Sauer,Karen J. Brasel,Eileen M. Bulger,John G. Myers,Herb A. Phelan,Louis H. Alarcon,John B. Holcomb +14 more
TL;DR: DNR orders were instituted after the 24-hour period of highest mortality risk and more often in older patients not in severe shock and in multivariable Cox models that accounted for time-varying blood product ratios, the associations were consistent, regardless of whether outcome was defined as mortality or the composite.