C
Charlotte Buckley
Researcher at Strathclyde Institute of Pharmacy and Biomedical Sciences
Publications - 34
Citations - 375
Charlotte Buckley is an academic researcher from Strathclyde Institute of Pharmacy and Biomedical Sciences. The author has contributed to research in topics: Medicine & Endothelial stem cell. The author has an hindex of 9, co-authored 26 publications receiving 246 citations. Previous affiliations of Charlotte Buckley include British Heart Foundation & University of Edinburgh.
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Journal ArticleDOI
Human kidney pericytes produce renin
Ania Stefanska,Christopher J Kenyon,Helen C. Christian,Charlotte Buckley,Isaac Shaw,John J. Mullins,Bruno Péault,Bruno Péault +7 more
TL;DR: The results confirm and extend the recently discovered developmental plasticity of microvascular pericytes, and may open new perspectives to the therapeutic regulation of the renin-angiotensin system.
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Increased Vascular Contractility in Hypertension Results From Impaired Endothelial Calcium Signaling.
TL;DR: This research presents a novel probabilistic approach that allows us to assess the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for other animals.
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Heterogeneity and emergent behaviour in the vascular endothelium.
TL;DR: Evidence is highlighted that shows that neighbouring endothelial cells are highly heterogeneous and display different sensitivities to various activators, which bestow capabilities on the endothelial collective that far exceed those of individual cells.
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Mitochondrial ATP production provides long-range control of endothelial inositol trisphosphate–evoked calcium signaling.
Calum Wilson,Matthew D. Lee,Helen R. Heathcote,Xun Zhang,Charlotte Buckley,John M. Girkin,Christopher D. Saunter,John G. McCarron +7 more
TL;DR: High-resolution, wide-field fluorescence imaging was used to investigate the regulation of Ca2+ signaling by mitochondria in large numbers of endothelial cells (∼50 per field) in intact arteries from rats and found that endothelial mitochondria were mobile and moved throughout the cytoplasm.
Journal ArticleDOI
Precise spatio-temporal control of rapid optogenetic cell ablation with mem-KillerRed in Zebrafish
Charlotte Buckley,Mariana T. Carvalho,Laura K. Young,Sebastian Rider,Clare McFadden,Caroline Berlage,Rachel F. Verdon,Jonathan M. Taylor,John M. Girkin,John J. Mullins +9 more
TL;DR: It is demonstrated that cell-specific genetically encoded photosensitizing proteins permit spatiotemporal optogenetic ablation with low-power laser light and significantly increase the speed of optoablation as well as fish survival.