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Bruno Péault
Researcher at University of Edinburgh
Publications - 271
Citations - 22537
Bruno Péault is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Stem cell & Mesenchymal stem cell. The author has an hindex of 65, co-authored 264 publications receiving 20291 citations. Previous affiliations of Bruno Péault include British Heart Foundation & Howard Hughes Medical Institute.
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Journal ArticleDOI
A perivascular origin for mesenchymal stem cells in multiple human organs
Mihaela Crisan,Solomon Yap,Louis Casteilla,Louis Casteilla,Chien Wen Chen,Mirko Corselli,Tea Soon Park,Gabriella Andriolo,Bin Sun,Bo Zheng,Li Zhang,Cyrille Norotte,Pang-ning Teng,Jeremy Traas,Rebecca C. Schugar,Bridget M. Deasy,Stephen F. Badylak,Hans-Jörg Bühring,Jean-Paul Giacobino,Lorenza Lazzari,Johnny Huard,Bruno Péault +21 more
TL;DR: Blood vessel walls harbor a reserve of progenitor cells that may be integral to the origin of the elusive MSCs and other related adult stem cells.
Journal ArticleDOI
Isolation of a candidate human hematopoietic stem-cell population
TL;DR: By extrapolation, the rare human Thy-1+Lin-CD34+ cell population contains pluripotent hematopoietic progenitors; it is proposed that it is highly enriched for candidate hematopolietic stem cells.
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Mesenchymal stem cell perspective: cell biology to clinical progress
Mark F. Pittenger,Dennis E. Discher,Bruno Péault,Donald G. Phinney,Joshua M. Hare,Arnold I. Caplan +5 more
TL;DR: The expansive and growing field of MSC research is teaching us basic human cell biology as well as how to use this type of cell for cellular therapy in a variety of clinical settings, and while much promise is evident, careful new work is still needed.
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A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells.
Koichi Ikuta,Tatsuo Kina,Ian MacNeil,Ian MacNeil,Nobuko Uchida,Bruno Péault,Yueh-hsiu Chien,Irving L. Weissman +7 more
TL;DR: The hypothesis that only fetal HSCs have the capacity to differentiate into V gamma 3+ T cells in the fetal thymic microenvironment is supported and that the developmental potential of H SCs may change during ontogeny is supported.
Journal ArticleDOI
Stem and progenitor cells in skeletal muscle development, maintenance, and therapy.
Bruno Péault,Michael A. Rudnicki,Yvan Torrente,Giulio Cossu,Jacques P. Tremblay,Terry Partridge,Emanuela Gussoni,Louis M. Kunkel,Louis M. Kunkel,Johnny Huard +9 more
TL;DR: Results suggest that purified pericytes and endothelium-related cells demonstrate high myogenic potential in culture and in vivo, and suggest their ultimate origin in blood vessel walls.